In Person Lecture: Synaptic Injury: A Link to the Past
Terrance Kummer, M.D., Ph.D.
Associate Professor of Neurology
Washington University School of Medicine In St. Louis
Director of the Neurotrauma ICU
Neurological and Neurosurgical intensive Care Unit
Timothy A. Johnson Medical Scholar Lecture: Synaptic Injury: A Link to the Past
March 31, 2023
1 to 2 p.m.
Location: Fralin Biomedical Research Institute at VTC, Room M203, 2 Riverside Circle, Roanoke, Virginia
Virtual attendance: Join via Zoom or watch the live webcast.
About this Seminar
Traumatic brain injury (TBI) is the number one global cause of neurological disability in the first half of life, while Alzheimer’s disease (AD) is the primary cause of dementia in the latter half. TBI, moreover, is the best established epigenetic risk factor for AD. What is the source of this connection, and how can it be severed? This seminar will discuss the role of synapses—subcellular nodes of communication between neurons and the strongest pathological correlate of cognitive decline in AD—in acute and chronic forms of brain injury. Synapses are challenging to study in situ owing to their small size and dense packing in the brain. Techniques pushing the boundaries of the data spectrum at both ends, such as super-resolution imaging and big data analytics, are opening new windows on synapses and their molecular and nanostructural features. Such studies may shed light on the apparent vulnerability of synapses to injury. This seminar will touch on two potentially important synaptic injury mechanisms, neuroinflammation and synaptic proteinopathies, and discuss their role in TBI and AD.
This is a free event hosted by the Fralin Biomedical Research Institute and the Virginia Tech Carilion School of Medicine. The Timothy A. Johnson Medical Scholar Lecture Series hosts clinician scientists who are exploring frontiers of medicine. These lectures are principally intended for Virginia Tech Carilion School of Medicine students and Virginia Tech students in the Translational Biology, Medicine, and Health graduate program. Virginia Tech and Carilion Clinic faculty, staff, and students may also attend.
You May Also Be Interested In...
Home ItemIn Person Seminar: Win to Fight and Lose to Flight: Innate Yet Flexible Aggression Circuit , home
March 24, 2023, 11 a.m. | Dayu Lin, Ph.D., Professor, Department of Psychiatry, Grossman School of Medicine, New York University | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Neurobiology Research
Home ItemSeminar: Signaling and Metabolic Control of Nucleotide Metabolism in Cancer , home
March 27, 2023, 11 a.m. | Eunus S. Ali, Ph.D., Postdoctoral Associate, Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University | Seminar
Home ItemIn Person Seminar: Quantifying Diverse Research Representation , home
March 31, 2023, 11:00 a.m. | Jonathan Jackson, Ph.D., Executive Director, Community Access, Recruitment, and Engagement (CARE) Research Center, Harvard University and Massachusetts General Hospital | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
Home ItemIn Person Lecture: Synaptic Injury: A Link to the Past , home
March 31, 2023, 1 p.m. | Terrance Kummer, M.D., Ph.D., Associate Professor of Neurology, Washington University School of Medicine in St. Louis | Timothy A. Johnson Medical Scholar Lecture Series
Home ItemSeminar: Understanding Cancer: From Development to Therapy , home
April 5, 2023, 11 a.m. | Biplab Dasgupta, M.S., Ph.D., MBA, Professor of Pediatrics, Division of Oncology, Cincinnati Children's Hospital | Seminar
Home ItemIn Person Seminar: Brain Dynamics and Flexible Behaviors , home
April 14, 2023, 11:00 am. | Lucina Q. Uddin, Ph.D., Professor in Residence, Department of Psychiatry and Biobehavioral Science, University of California, Los Angeles | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Addiction Recovery Research Center and Center for Health Behaviors Research