In Person Lecture: Synaptic Injury: A Link to the Past
Terrence Kummer, M.D., Ph.D.
Associate Professor of Neurology
Washington University School of Medicine In St. Louis
Director of the Neurotrauma ICU
Neurological and Neurosurgical intensive Care Unit
Barnes-Jewish Hospital
Timothy A. Johnson Medical Scholar Lecture: Synaptic Injury: A Link to the Past
March 31, 2023
1 to 2 p.m.
Location: Fralin Biomedical Research Institute at VTC, Room M203, 2 Riverside Circle, Roanoke, Virginia
Virtual attendance: Join via Zoom or watch the live webcast.
About this Seminar
Traumatic brain injury (TBI) is the number one global cause of neurological disability in the first half of life, while Alzheimer’s disease (AD) is the primary cause of dementia in the latter half. TBI, moreover, is the best established epigenetic risk factor for AD. What is the source of this connection, and how can it be severed? This seminar will discuss the role of synapses—subcellular nodes of communication between neurons and the strongest pathological correlate of cognitive decline in AD—in acute and chronic forms of brain injury. Synapses are challenging to study in situ owing to their small size and dense packing in the brain. Techniques pushing the boundaries of the data spectrum at both ends, such as super-resolution imaging and big data analytics, are opening new windows on synapses and their molecular and nanostructural features. Such studies may shed light on the apparent vulnerability of synapses to injury. This seminar will touch on two potentially important synaptic injury mechanisms, neuroinflammation and synaptic proteinopathies, and discuss their role in TBI and AD.
Additional Details
This is a free event hosted by the Fralin Biomedical Research Institute and the Virginia Tech Carilion School of Medicine. The Timothy A. Johnson Medical Scholar Lecture Series hosts clinician scientists who are exploring frontiers of medicine. These lectures are principally intended for Virginia Tech Carilion School of Medicine students and Virginia Tech students in the Translational Biology, Medicine, and Health graduate program. Virginia Tech and Carilion Clinic faculty, staff, and students may also attend.
You May Also Be Interested In...
-
Home Item
Seminar: Integrated Bioelectronic Systems for Biomedical Research and Healthcare: Materials, Electronics, and Computing , homeFeb. 7, 2023, 12 p.m. | Wei Ouyang, Ph.D., Postdoctoral Fellow, Querrey Simpson Institute for Bioelectronics, Northwestern University | Seminar
-
Home Item
Seminar: Molecular Targets of Prenatal Alcohol Exposure During Early Brain Development , homeFeb. 8, 2023, 2 p.m. | Karen Boschen, Ph.D., Postdoctoral Research Associate, Bowles Center for Alcohol Studies, University of North Carolina School of Medicine | Seminar
-
Home Item
In Person Lecture: Developmental Cognitive Neuroscience in the Era of Big Data , homeFeb. 9, 2023, 5:30 p.m. (Reception at 5 p.m.) | Damien Fair, PA-C, Ph.D., Professor, Institute of Child Development, Department of Pediatrics, College of Education and Human Development, University of Minnesota Medical School | Maury Strauss Distinguished Public Lecture
-
Home Item
In Person Seminar: Pathogenic Mechanisms and Novel Therapies for Immune Neoplasms , homeFeb. 10, 2023, 11 a.m. | Ari Melnick, M.D., Gebroe Family Professor of Hematology/Oncology, and Director, Sackler Center for Biomedical and Physical Sciences, Weill Medical College, Cornell University | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Cancer Research Group
-
Home Item
In Person Seminar: Behavioral Economic Approaches for Measuring Substance Use Severity and Motivating Change , homeFeb. 17, 2023, 11:00 am. | James G. Murphy, Ph.D., Professor, Department of Psychology, University of Memphis | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Addiction Recovery Research Center and Center for Health Behaviors Research
-
Home Item
In Person Seminar: Functional MRI of Dynamic Physiological States , homeFeb. 24 2023, 11:00 a.m. | Catherine Chang, Ph.D., Assistant Professor, Department of Electrical Engineering and Computer Science, Vanderbilt University | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research