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Virtual Seminar: Mammalian 12-hour Clock Regulation of Lipid Homeostasis in Liver Physiology and Diseases

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Meng Huan, Ph.D.

Meng Huan, M.B., Ph.D.

Senior Research Fellow
Department of Molecular and Cellular Biology
Baylor College of Medicine

Candidate for Obesity and Metabolism Faculty Position

Virtual Seminar: Mammalian 12-hour Clock Regulation of Lipid Homeostasis in Liver Physiology and Diseases

Date: Jan. 24, 2022

Time:  12:00 p.m. - 1:00 p.m.

Virtual Access: Watch this lecture live via Zoom, or on our Live Webcast page

About this Seminar

Dr. Meng’s lab work centers on the mechanism of the early-life metabolic regulation and clock control in physiology and their dysregulation in metabolic diseases, cancer metabolism, and aging. One major area of his research is focused on studying the contributions of a newly uncovered 12-hour circatidal clock to the metabolic development and progression toward metabolic diseases (e.g., nonalcoholic fatty liver disease, NAFLD), obesity and cancer. Dr. Meng and his team recently discovered and published on the existence of an evolutionarily conserved circatidal 12-hour clock and its regulation of lipid metabolism that is: 1) independent of the 24-hour circadian clock, 2) cell autonomous and 3) regulated by molecular pacemakers that are distinct from those that control the 24-hour circadian clock. Dr. Meng’s new research program also targets the mechanisms connecting biological clocks with metabolism at all levels in response to various nutritional and environmental changes, from cellular organelles to the whole organism, and will specifically address a question of how the temporal-spatial (4D) deregulation of this clock–metabolic crosstalk can lead to various pathologies.

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