Seminar: Signaling and Metabolic Control of Nucleotide Metabolism in Cancer
Eunus S. Ali, Ph.D.
Postdoctoral Associate
Department of Biochemistry and Molecular Genetics
Feinberg School of Medicine
Northwestern Univeristy
Candidate for Cancer Research Faculty Position
Seminar: Signaling and Metabolic Control of Nucleotide Metabolism in Cancer
Date: March 27, 2023
Time: 11 a.m.
Location: Room R3012, 2 Riverside Circle
Virtual attendance: Join via Zoom.
About this Seminar
It is known for many years that oncogenes are mainly responsible for the dysregulated metabolism in cancer cells. However, how the oncogenes or mutated genes promote the cancer cell metabolism - we know very little about those mechanisms. In his postdoctoral work, employing high-resolution mass spectrometry, biochemical approaches and genome editing technology CRISPR, Dr. Ali has identified two important regulatory mechanisms by which cancer cells stimulate nucleotide synthesis to boost their biomass and growth compared to normal cells. This work advances our understanding of metabolic biology of tumor cells and promotes our ability to identify the key molecular links between oncogenic signaling and cellular metabolism.
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