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News from the Office of the Executive Director:
October, 2020
Dear colleagues, community members, and friends,

Within the past few weeks, our faculty members have published two exciting studies that reveal dopamine and serotonin's role in human perception and decision-making, and how chronic jet lag conditions alter our biological rhythms and may promote cancer growth.  Published in high-impact journals (Neuron and Science Advances), these discoveries represent the high caliber, creativity and peer recognition of our faculty, staff, and students. 

We're also continuing to expand our team of primary faculty, and intend to scale up by 20 to 25 more research teams by 2027. We've already onboarded  Scott Johnstone, Ph.D. and Jenny Munson, Ph.D., and are actively recruiting cardiovascular scientists to establish laboratories in our newest Fralin Biomedical Research Institute building and neuroscientists to join the research institute. 

We invite you to tune into the first of an ongoing virtual panel series with our researchers, "Virginia Tech Cancer Research Alliance: Uniting Technology, Resources and People for Innovations to End Cancer" on Nov. 10, and our upcoming Maury Strauss Distinguished Public Lecture, "Can We Ever Really ‘See' Pain? Unravelling Pain’s Mysteries with Neuroimaging," on Nov. 19.


In the spirit of Ut Prosim,

Michael J. Friedlander, Ph.D.

Executive Director, Fralin Biomedical Research Institute at VTC
Vice President for Health Sciences and Technology, Virginia Tech
RECENT NEWS 
The race against cancer’s clock: New study shows chronic jet lag impairs immune response, accelerates tumor growth

A new study published Oct. 14 in Science Advances reveals that chronic circadian disruptions alter the microenvironment surrounding cancer cells, making it more favorable for tumor growth, and also hinders the body’s natural immune defenses. Read More
Scientists find dopamine, serotonin have unexpectedly profound roles in the human brain

In first-of-their-kind observations in the human brain, an international team of researchers has revealed two well-known neurochemicals — dopamine and serotonin — are at work at sub-second speeds to shape how people perceive the world and take action based on their perception. Read More
Scientists advance understanding of blood-brain barrier health with implications for brain disease

In a study with potential impacts on a variety of neurological diseases, Virginia Tech researchers have provided the first experimental evidence from a living organism to show that an abundant, star-shaped brain cell known as an astrocyte is essential for blood-brain barrier health.  Read More
Graduate student receives highly competitive NIH award to fuse immunology and neuroscience research

Gabriela Carrillo, a Virginia Tech translational biology, medicine, and health (TBMH) doctoral candidate, has been awarded a six-year $445,000 National Institutes of Health award that will fund her remaining predoctoral research in the Fox Lab, as well as her postdoctoral research. The award supports exceptional graduate students who are interested in pursuing careers as independent researchers. Read More
Swallowing difficulties in children with developmental disorders may be due to misfiring brain cells

Misfiring brain cells that control key parts of the mouth and tongue may be creating swallowing difficulties in children with neurodevelopmental disorders, according to neuroscientists with Virginia Tech and George Washington University. In research using a mouse model of a genetic childhood disorder known as DiGeorge syndrome, scientists found brain cells called motor neurons that directly control the tongue muscles were firing spontaneously, out of sync with the mechanisms that should control their activity. Read More
UPCOMING PUBLIC EVENTS
Researcher Panel Discussion
Nov. 10: Virginia Tech Cancer Research Alliance - Uniting Technology, Resources and People for Innovations to End Cancer
Speakers: Michael Friedlander, Ph.D., Jenny Munson, Ph.D., Carla Finkielstein, Ph.D., and Eli Vlaisavljevich, Ph.D.
Virtual Maury Strauss Distinguished Public Lecture
Nov. 19: Can We Ever Really ‘See' Pain? Unravelling Pain’s Mysteries with Neuroimaging
Speaker: Irene Tracey, MA, D.Phil., FRCA, FMedSci
Virtual Maury Strauss Distinguished Public Lecture
Dec. 3: Reconciling Privacy and Accountability: the Context of COVID-19
Speaker: Anita A. Allen, J.D., Ph.D.
Virtual Maury Strauss Distinguished Public Lecture
Feb. 25: Religious Leaders as Trusted Messengers for Eliminating HIV/AIDS
Speaker: A. Oveta Fuller, Ph.D.
STUDENT ACHIEVEMENTS

Alyssa Brunal-Brown (left) and Amnah Eltahir successfully defend doctoral dissertations

Brunal-Brown, a Translational Biology, Medicine, and Health graduate student who works in associate professor Albert Pan's laboratory, defended her dissertation, Effects of Constitutive and Acute Connexin 36 Deficiency On Brain-wide Susceptibility to PTZ-induced Neuronal Hyperactivity. Eltahir, a graduate student in Virginia Tech and Wake Forest University's School of Biomedical Engineering and Sciences who works in professor Read Montague's laboratory, defended her dissertation, Novel Electrochemical Methods for Human Neurochemistry, on Sept. 23. Congratulations! 
 
HOW YOU CAN HELP

Making transformative discoveries to build a healthier future for all

Virginia Tech and the Fralin Biomedical Research Institute are providing rapid COVID-19 sample analysis to help control the pandemic in support of our local community, the Commonwealth, and frontline responders. Private support is critical to continue these efforts. Here are some ways that you can support the research institute right now, in light of COVID-19:
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