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Novel Electrochemical Methods for Human Neurochemistry

Graduate Student Dissertation Defense presented by the Fralin Biomedical Research Institute at VTC

Novel Electrochemical Methods for Human Neurochemistry

Date: Sept. 23, 2020
Time: 1:00 p.m. 
Virtual Access: 
To join the audience for this dissertation defense, please email the candidate directly to obtain the Zoom videoconference link at

About This Dissertation 

Neuroscience characterizes nervous system functions from the cellular to the systems level. A gap in available technologies has prevented neuroscientist from studying how changes in the molecular dynamics in the brain relate to psychiatric conditions. Recent efforts by the Montague Laboratory have adapted neurochemistry techniques for use in human patients. Consequently, a new “random burst sensing” approach was developed that challenged existing assumptions about electrochemistry. In this study, in-vivo experiments were conducted to push the limits of electrochemical sensing by reducing the voltage amplitude range and increasing sensing temporal resolution of electrochemical sensing beyond previously established limits. The results of this study offer novel neurochemistry approaches and act as a jumping off point for future technological developments.


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