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Our Labs

Our Laboratories

Fralin Biomedical Research Institute faculty conduct research in wet and dry labs in our 280,000-square-foot facilities

Lab at Fralin Biomedical Research Institute
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    Bickel Lab
    Bickel Lab , home

    The Bickel Lab studies dysfunctional decision-making and interventions to help people battling addiction make healthier choices.

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    Chappell Lab
    Chappell Lab , home

    The Chappell Lab studies how the blood vasculature develops during early organ formation and during certain diseases such as tumor progression and neurological disorders.

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    Chiu Lab
    Chiu Lab , home

    The Chiu Laboratory examines the neuroscience of human motivation and social decision-making.

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    DeLuca Lab
    DeLuca Lab , home

    The DeLuca lab has examined the impact of intensive neurorehabilitation treatments on children and adults with neuromotor impairments for more than 25 years.

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    DiFeliceantonio Lab
    DiFeliceantonio Lab , home

    Dr. DiFeliceantonio's laboratory uses multimodal imaging and metabolic measures to study how the brain integrates peripheral signals to guide food motivation, choice, and eating behavior.

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    Farris Lab
    Farris Lab , home

    The Farris Lab studies how neurons respond during learning and how those responses differ between genetically distinct cell types thought to be required for storing memories.

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    Finkielstein Lab
    Finkielstein Lab , home

    The Finkielstein Lab studies how the molecules that dictate a cell's life cycle influence cancer initiation and progression.

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    Fox Lab
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    The Fox Laboratory studies the mechanisms underlying synaptic targeting and synaptic differentiation, focusing on the visual system.

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    Friedlander Lab
    Friedlander Lab , home

    The Friedlander Lab uses quantitative single neuron patch clamp electrophysiological methods and imaging to see structural changes in the calcium signals that underlie synaptic function.

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    Gourdie Lab
    Gourdie Lab , home

    The Gourdie Lab studies subunit proteins called connexins, which are located in gap junctions that enable direct communication between cells.

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    Horn Lab
    Horn Lab , home

    Kimberly Horn studies methods to prevent drug use to help address tobacco use and, more recently, the opioid crisis in central Appalachia.

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    Howell Lab
    Howell Lab , home

    The Howell Lab studies ways to improve mother-infant health outcomes by exploring the factors that influence healthy infant brain and behavioral development.

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    Johnstone Lab
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    The Johnstone Lab focuses on understanding how healthy blood vessels are altered in disease and defining effective pathways to therapeutically target vascular disease.

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    King-Casas Lab
    King-Casas Lab , home

    The King-Casas Lab addresses two broad areas of inquiry: (1) neural underpinnings of valuation and learning in social settings, and (2) how social and economic preferences influence valuation and learning.

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    LaConte Lab
    LaConte Lab , home

    Research in the LaConte lab is devoted to advanced neuroimaging acquisition and data analysis approaches, aimed at basic scientific discovery as well as understanding and rehabilitating neurological and psychiatric diseases.

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    LaMantia Lab
    LaMantia Lab , home

    The LaMantia Lab studies the genetics underlying neural development to identify new diagnostic and therapeutic approaches for a broad range of disorders that compromise brain and organ system development.

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    Lamouille Lab
    Lamouille Lab , home

    The Lamouille Lab studies ways to deregulate cancer cell communication and is developing new therapeutic strategies to stall cancer stem cell proliferation and metastases.

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    Montague Lab
    Montague Lab , home

    The Montague Lab's work focuses on computational neuroscience – the connection between physical mechanisms present in real neural tissue and the computational functions that these mechanisms embody.

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    Morozov Lab
    Morozov Lab , home

    The Morozov Lab studies the neuronal circuits associated with empathy and examines how these circuits become altered in pathological conditions related to post-traumatic stress disorder, depression, psychopathy, autism, and schizophrenia.

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    Mukherjee Lab
    Mukherjee Lab , home

    The Mukherjee Lab studies the role of MAGUK (Membrane Associated Guanylate Kinase) proteins in neurodevelopment.

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    Munson Lab
    Munson Lab , home

    The Munson Lab studies the tumor microenvironment in cancers, including glioblastoma, the deadliest form of brain cancer. Our research focuses on the emerging research area of fluid flow.

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    Pan Lab
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    The Pan Lab aims to elucidate the general principles of vertebrate development and uncover the genetic and developmental causes of human neurological and psychiatric disorders.

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    Parker Lab
    Parker Lab , home

    The Parker Lab conducts basic and translational research into the performance of health care teams in numerous clinical domains, including the ICU, operating room, and outpatient clinical practice.

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    Poelzing Lab
    Poelzing Lab , home

    The Poelzing Lab studies the electrical activity of the heart through cardiac myocytes and proteins and how abnormalities are linked to sudden cardiac death.

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    C. Ramey Lab
    C. Ramey Lab , home

    The Ramey Lab's program of research centers on the role of experience – across the human lifespan - in the development of competence and robust health.

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    S.L. Ramey Lab
    S.L. Ramey Lab , home

    The Landesman Ramey Lab addresses the contribution of early experience from before conception to later health and development and the development and testing of highly promising treatments for children with disabilities and at-risk conditions.

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    Robel Lab
    Robel Lab , home

    The Robel Lab's research interest is in the role of astrocytes, star-shaped glial cells, in the development and progression of CNS diseases.

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    Sheng Lab
    Sheng Lab , home

    Researchers in the Sheng Laboratory are particularly interested in glioblastoma multiforme.

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    Shin Lab
    Shin Lab , home

    The Shin Lab aims to understand the role of brain circuit-specific mechanisms using translationally relevant animal models of stress-induced psychiatric diseases.

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    Smyth Lab
    Smyth Lab , home

    The Smyth Laboratory studies cardiomyopathy at a subcellular level, searching for potential targets for therapeutic interventions to help restore normal cardiac function to diseased hearts.

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    Sontheimer Lab
    Sontheimer Lab , home

    The Sontheimer Lab researches the biology of glial cells, the brain's most abundant cell type. Harald Sontheimer is credited with making foundational discoveries on the functional properties of glial cells in the brain.

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    Stein Lab
    Stein Lab , home

    The Stein Lab's research interests include behavioral economics, neuroeconomics, addiction, obesity, and health behavior.

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    Swanger Lab
    Swanger Lab , home

    The Swanger Lab studies subtypes within a glutamate receptor family, called N-methyl-D-aspartate receptors (NMDAR), located in the brain's thalamus to understand the origins of seizures.

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    Warren Lab
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