Amo Lab

By combining anatomy, physiology, behavior, computational modeling, and molecular tools, the Amo Lab, led by principal investigator Ryunosuke Amo, Ph.D., aims to identify the direct inputs to dopamine neurons that are critical for generating diverse dopamine signals; investigate how opioid abuse alters these diverse dopamine signals and determine which circuits are responsible; and elucidate how diverse dopamine signals have evolved across vertebrate evolution. Through this research, Dr. Amo aims to uncover the neural circuit mechanisms underlying the generation of diverse dopamine signals and their evolutionary origins.