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An infant participating in the Baby CHAMP study

March 12, 2026

Intensive therapy approaches show benefits for infants and toddlers with cerebral palsy

Infants and toddlers with unilateral cerebral palsy, which affects the brain’s control of muscles on one side of the body, show lasting improvements in hand and arm function when they receive early, high-dose therapy, according to a new multisite clinical trial led by Virginia Tech researchers at the Fralin Biomedical Research Institute at VTC.

The Baby CHAMP study — short for Children with Hemiparesis Arm-and-Hand Movement Project — directly compared three therapist-delivered interventions: two forms of constraint-induced movement therapy, which limit the stronger arm to encourage use of the weaker one when combined with therapy, and bimanual therapy, which promotes coordinated use of both hands.

The researchers found that children ages 6 to 24 months showed similar gains whether therapy involved full-time casting, a splint worn during sessions, or bimanual training without constraining the stronger arm.

Published in Pediatrics Open Science, the study addresses a long-standing gap in clinical evidence. 

 

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    April 16, 2026, 5:30 p.m. (Reception at 5 p.m.) | Lewis Lanier, Ph.D., J. Michael Bishop Distinguished Professor and Chair Emeritus, Department of Microbiology and Immunology, University of California, San Francisco; Elected Member, National Academy of Sciences | Maury Strauss Distinguished Public Lecture

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The Fralin Biomedical Research Institute at VTC is one of the nation’s fastest-growing academic biomedical research enterprises and a destination for world-class biomedical, behavioral, and computational researchers focused on advancing scientific understanding of human health through groundbreaking research in preventing, diagnosing, and treating the world’s leading causes of death and suffering.

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Your generous support of the Fralin Biomedical Research Institute's rigorous biomedical research enterprise makes a difference for our faculty, students, and patients. Every donation helps accelerate the pace of new discoveries to help patients with cancer, neurological disorders, heart disease, and even rare genetic disorders. Private donations fast-track our progress.