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Featured Story

Sora Shin, Ph.D.

Nov. 5, 2025

Brain pathway may fuel both aggression, self-harm

Aggression and self-harm often both occur in individuals with a history of early-life trauma — a connection that has largely been documented by self-reporting in research and clinical settings.

Adding to this connection, individuals treated for self-inflicted injuries are five times more likely to engage in excessive aggression.

What’s happening in the brain to tie these two behaviors together?

A new Virginia Tech study by Sora Shin, assistant professor in the Fralin Biomedical Research Institute at VTC’s Center for Neurobiology Research, has identified a brain circuit that changes after trauma. The study was published Nov. 5 in Science Advances.

 

Campus news

Creating a healthier future. For everyone.

The Fralin Biomedical Research Institute at VTC is one of the nation’s fastest-growing academic biomedical research enterprises and a destination for world-class researchers. The institute’s Virginia Tech scientists focus on diseases that are the leading causes of death and suffering in the United States, including brain disorders, heart disease, and cancer. Since its founding in 2010, the research institute has experienced unprecedented growth: doubling its enterprise and lab facilities in Roanoke, while also investing in brand-new laboratories on the Children’s National Research & Innovation Campus in Washington, D.C.

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Giving to the Research Institute

Your generous support of the Fralin Biomedical Research Institute's rigorous biomedical research enterprise makes a difference for our faculty, students, and patients. Every donation helps accelerate the pace of new discoveries to help patients with cancer, neurological disorders, heart disease, and even rare genetic disorders. Private donations fast-track our progress.