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Inheriting Chromatin Domains in Mammals and the Mechanisms Involved

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Thelma Escobar, Ph.D.

Thelma Escobar, Ph.D.

Assistant Professor
Department of Biochemistry
Institute for Stem Cell & Regenerative Medicine
University of Washington
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Pioneers in Biomedical Research Seminar

Inheriting Chromatin Domains in Mammals and the Mechanisms Involved

Date: Sept. 5, 2025

Time: 11 a.m. to noon

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About this Seminar

A long-term goal of the Escobar Lab is to understand the mechanisms and functional consequences of chromatin dynamics in maintaining cellular identity. The lab is merging chromatin dynamics, stem cells, and immune biology to study epigenetic inheritance. One interest of the lab is to examine how histone chaperones facilitate the inheritance of chromatin domains across DNA replication and in immune cell development. In this presentation, Dr. Escobar will describe mechanisms for inheritance of facultative heterochromatin and how misregulation of histone chaperone function can result in cancer.

Additional Details

This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Cancer Research Center — D.C. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.

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