Opposing Activities of Chromatin Modifiers in Balancing Stem Cell Division, Differentiation, and Death
Jamy Peng, Ph.D.
Associate Member
Department of Developmental Neurobiology
Comprehensive Cancer Care Center
St. Jude Children's Research Hospital
Pioneers in Biomedical Research Seminar: Opposing Activities of Chromatin Modifiers in Balancing Stem Cell Division, Differentiation, and Death
Date: Oct. 7, 2022
Time: 11 a.m. - 12 p.m.
About this Seminar
Neural stem cell division, neurogenesis, and gliogenesis give rise to all cells in the brain. Dr. Peng's lab studies the modifiers of histone H3 lysine 27 (H3K27), which regulate genetic programs for neural stem cell amplification and differentiation. Dysfunction in H3K27 modifiers lead to developmental disorders and pediatric brain tumors. The lab has uncovered regulators of these H3K27 modifiers that control stem cell division, differentiation, and death. These advances illuminate epigenetic regulation of neural stem cells and pathogenic mechanisms in brain defects and malignancy.
Additional Details
This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Cancer Research Group. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.
You May Also Be Interested In...
-
Home Item
A Novel Bispecific Antibody to Target the Brain Tumor Microenvironment , homeMay 2, 2025, 11:00 a.m. | Khuson Yun, Ph.D., Associate Professor, Department of Neurology, Houston Methodist Chair, Neurodegenerative Disease Research, Houston Methodist Research Institute, Weill Cornell Medical College | Co-Sponsored by the Fralin Biomedical Research Institute Cancer Research Center – Roanoke
-
Home Item
Transformation of Information from the External World by Cortical Circuits During Learning , homeMay 9, 2025, 11:00 a.m. | Alison Barth, Ph.D., Professor, Department of Biological Sciences, Carnegie Mellon University | Co-Sponsored by the Center for Neurobiology Research, Fralin Biomedical Research Institute
-
Home Item
The Role of Exercise in Memory Function , homeMay 23, 2025, 11:00 a.m. | Henriette van Praag, Ph.D., Associate Professor, Department of Biomedical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University | Co-Sponsored by the Center for Exercise Medicine Research, Fralin Biomedical Research Institute
-
Home Item
Pathways and Regulation of Cardiac Nav1.5 Channel Trafficking in Adult Myocytes , homeMay 30, 2025, 11:00 a.m. | Gea-Ny Tseng, Ph.D., Professor, Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine | Co-Sponsored by the Fralin Biomedical Research Institute Center for Vascular and Heart Research
-
Home Item
Targeting Acquired Dependencies During Tumor Evolution , homeJune 6, 2025, 11:00 a.m. | Kris Wood, Ph.D., Associate Professor, Department of Pharmacology and Cancer Biology, Duke University School of Medicine | Co-Sponsored by the Fralin Biomedical Research Institute Cancer Research Center – D.C.