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Understanding Vascular Morphogenesis and Morphology: Live Insights from Zebrafish

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Arndt F. Siekmann, Ph.D.

Arndt F. Siekmann, Ph.D.

Associate Professor, Cell and Developmental Biology
Perelman School of Medicine
University of Pennsylvania
Pioneers in Biomedical Research Seminar

Understanding Vascular Morphogenesis and Morphology: Live Insights from Zebrafish

Date: Nov. 21, 2025

Time: 11 a.m. to noon

In-person: 4 Riverside, G101 A/B

Virtual: Watch via Zoom

About this Seminar

The mechanisms driving the morphogenesis of hierarchically patterned vascular networks are far from understood. Using live imaging in zebrafish, Siekmann's lab discovered that distinct morphogenetic principles underlie the formation of arteries and veins. They also found that endothelial cells lining arteries and veins differ in their morphologies. The lab is currently investigating how these morphologies control vascular function and the genetic pathways underlying proper vascular patterning.

Additional Details

This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Center for Vascular and Heart Research. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.

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