In Person Seminar: Deciphering the Metabolic Origins of Heart Failure: Towards Novel Therapeutic Targets
Daniel Kelly, Ph.D.
Willard and Rhoda Ware Professor
Director
Penn and CHOP Cardiovascular Institutes
Perelman School of Medicine
University of Pennsylvania
Children's Hospital of Philadelphia
Pioneers in Biomedical Research Seminar: Deciphering the Metabolic Origins of Heart Failure: Towards Novel Therapeutic Targets
Date: March 22, 2024
Time: 11 a.m. - 12 p.m.
About this Seminar
During the development of heart failure, the myocardium undergoes fuel metabolic reprogramming that reduces the capacity for ATP production. This ultimately leads to an “energy starvation” that contributes to the pathogenesis of heart failure. The Kelly Lab has delineated the transcriptional regulatory circuitry that controls mitochondria function and fuel oxidation in the developing heart. In addition, metabolomic and proteomic profiling has identified nodal points for re-balancing the metabolic derangements of the failing heart. Dr. Kelly’s presentation will cover these topics.
Additional Details
This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Center for Vascular and Heart Research. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.
You May Also Be Interested In...
-
Home ItemIn Person Seminar: Regulation of Mitochondrial Parameters in Skeletal Muscle , home
May 3, 2024, 11:00 a.m. | Glenn Rowe, Ph.D., Associate Professor of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham | Co-Sponsored by the Fralin Biomedical Research Institute Center for Exercise Medicine Research
-
Home ItemPlanning the Future of Environmental Health Sciences , home
May 9, 2024, 5:30 p.m. (Reception at 5 p.m.) | Rick Woychik, Ph.D., Director, National Institute of Environmental Health Sciences, National Institutes of Health | Maury Strauss Distinguished Public Lecture
-
Home ItemIn Person Seminar: Flavors in Tobacco and Nicotine Products: Science-based Regulation , home
May 10, 2024, 11:00 a.m. | Suchitra Krishnan-Sarin, Ph.D., Albert E. Kent Professor of Psychiatry, Yale School of Medicine | Co-Sponsored by the Fralin Biomedical Research Institute Center for Health Behaviors Research and the Addiction Recovery Research Center
-
Home ItemCANCELLED: In Person Seminar: Sex Influences on Brain and Body: An Issue That is Here to Stay , home
May 17, 2024, 11:00 a.m. | Larry Cahill, Ph.D., Professor, Neurobiology and Behavior, University of California, Irvine | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
-
Home ItemIn Person Seminar: Continuous Decision-Making , home
May 17, 2024, 11:00 a.m. | Benjamin Hayden, Ph.D., Professor and McNair Scholar of Neurosurgery, Baylor College of Medicine | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
-
Home ItemIn Person Seminar: Three Photon Imaging of Active Neural Networks During Visual Processing in the Living Brain , home
May 31, 2024, 11:00 a.m. | Prakash Kara, Ph.D., Professor, Department of Neuroscience, University of Minnesota Medical School | Co-Sponsored by the Executive Director, Fralin Biomedical Research Institute