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Center for Heart and Reparative Medicine Research

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CENTER FOR HEART AND
REPARATIVE MEDICINE RESEARCH

     

About the Center for Heart and Reparative Medicine Research

The Fralin Biomedical Research Institute Center for Heart and Reparative Medicine Research serves as a nexus for cardiovascular research teams exploring basic research questions about the heart. With heart disease the nation’s leading killer, these teams are working to understand how the heart develops, how it becomes damaged, and, ultimately, how it can be repaired. They are also mapping out fundamental properties of the heart, such as how it conducts electricity. Together, they are delving into new strategies for healing the heart.

Contacts

  • Center for Heart and Reparative Medicine Research Director: Robert Gourdie, Ph.D. 
  • Center for Heart and Reparative Medicine Research and Administrative Coordinator: Linda Collins
  • Arrhythmia: Irregular heart beat
  • Acute Ischemia: Heart attack
  • Cardiac Conduction: Heart beats
  • Cardiomyopathy: Thickened heart tissue
  • Infection: How viruses affect cellular function and signaling in the heart
  • Ephaptic Coupling: Electrical channels that connect heart muscle cells across a vat of fluid
  • Gap Junctional Coupling: Signaling channels that structurally connect two cells
  • Sudden Cardiac Death: When cardiac conduction fails
  • Vascular Microbiology: How blood vessels grow and respond to injury

 

CENTER FOR GLIAL BIOLOGY IN 
HEALTH, DISEASE, AND CANCER LABS
 

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    Chappell Lab
    Chappell Lab , home

    The Chappell Lab studies how the blood vasculature develops during early organ formation and during certain diseases such as tumor progression and neurological disorders.

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    Gourdie Lab
    Gourdie Lab , home

    The Gourdie Lab studies subunit proteins called connexins, which are located in gap junctions that enable direct communication between cells.

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    Johnstone Lab
    Johnstone Lab , home

    The Johnstone Lab focuses on understanding how healthy blood vessels are altered in disease and defining effective pathways to therapeutically target vascular disease.

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    Lamouille Lab
    Lamouille Lab , home

    The Lamouille Lab studies ways to deregulate cancer cell communication and is developing new therapeutic strategies to stall cancer stem cell proliferation and metastases.

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    Poelzing Lab
    Poelzing Lab , home

    The Poelzing Lab studies the electrical activity of the heart through cardiac myocytes and proteins and how abnormalities are linked to sudden cardiac death.

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    Smyth Lab
    Smyth Lab , home

    The Smyth Laboratory studies cardiomyopathy at a subcellular level, searching for potential targets for therapeutic interventions to help restore normal cardiac function to diseased hearts.

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UPCOMING EVENTS

Presented by the Fralin Biomedical Research Institute and co-hosted by the Center for Heart and Reparative Medicine Research