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CORE SERVICES

     

The Fralin Biomedical Research Institute 3D Printing Lab is a self-service facility, available to all faculty, staff, and researchers on a first-come, first-served basis.

Location: 
Room 1002, 4 Riverside Circle, Roanoke, VA

Facility Contacts:
Thomas Wertalik (wertalik@vtc.vt.edu, 540-526-2270)
Sarah Glenn (sglenn@vtc.vt.edu, 540-526-2014) 

3D Printer

This lab is certified for handling of specimens infected with indigenous or exotic agents, agents that present a potential for aerosol transmission, and agents causing serious or potentially lethal disease.

Location: 
4 Riverside Circle, Roanoke, VA
This is a secured area. Please contact facility staff to arrange access.

Facility Contacts:
Michael Zeitz, Ph.D (mjzeitz@vtc.vt.edu, 540-526-2239)
James Smyth, Ph.D. (smyth@vtc.vt.edu, 540-526-2238)

ABSL3

The Behavioral Testing Facility contains four small suites equipped for comprehensive behavioral testing of research subjects. The behavioral paradigms performed in the core include tests for cognitive, emotional, social, and motor functions. This is a self-service facility. 

Location: 
Room 1089, 2 Riverside Circle, Roanoke VA

Facility Contact:
Alexei Morozov, Ph.D. (alexeim@vtc.vt.edu, 540-526-2021)

The lab's Cellink BIO X bioprinter is used to culture cells for applications in tissue engineering, drug discovery, and toxicity research. 

Location: 

Room 1411A, 4 Riverside Circle, Roanoke VA

Facility Contacts:
John Chappell, Ph.D. (jchappell@vtc.vt.edu, 540-526-2219)
Jenny Munson, Ph.D. (munsonj@vt.edu, 540-526-2238)

Bio X Bioprinter
[Image source: Cellink]

The institute's Siemens Somatom Confidence RT Pro CT Scanner is used in human and companion animal research. 

Location: 
Room G407, 4 Riverside Circle, Roanoke, VA

CT large bore
[Image source: Siemens]

The Bruker Micro PET/CT Si78 allows 18F-FDG PET and 2D and 3D CT imaging applications. 

Location: 
Room G411, 4 Riverside Circle, Roanoke VA

Facility Contacts:
Maosen Wang, Ph.D. (maosen@vtc.vt.edu, 540-526-2371)
Jenny Munson, Ph.D. (munsonj@vt.edu, 540-526-2238)

Bruker MicroPET/CT Si78

The Bio-Rad Droplet Digital PCR is available for absolute quantification of transcripts, detection of rare mutations, genome editing, gene expression analysis at the single cell level, and other uses.

Location: 

Room R1090, 2 Riverside Circle, Roanoke VA

Facility Contact:
Chandra Bain (cebaker@vtc.vt.edu, 540-526-2632)

Droplet reader

The Accuri C6 Flow Cytometer provides provides rapid multi-parametric analysis of single cells in solution.

Location: 

Room R1090, 2 Riverside Circle, Roanoke VA

Facility Contact:
Chandra Bain (cebaker@vtc.vt.edu, 540-526-2632)

flow cytometer

The Sony SH800 Cell Sorter can both analyze and sort cell populations.

Location: 

Room R1090, 2 Riverside Circle, Roanoke VA

Facility Contact:
Chandra Bain (cebaker@vtc.vt.edu, 540-526-2632)

cell sorter

The INSIGHTEC Exablate Neuro V2 Focused Ultrasound System can deliver ultrasound engergy deep in the brain to create a lesion with no incisions. Focused ultrasound is guided by magnetic resonance imaging (MRI). At the Fralin Biomedical Research Institute, the technology is paired with a Siemens MAGNETOM Prisma 3T imaging system that is part of the research institute's large bore MRI facilities.

*This facility is not yet operational

Location: 
Room G404, 4 Riverside Circle, Roanoke VA

Facility Contacts:
Maosen Wang, Ph.D. (maosen@vtc.vt.edu, 540-526-2371)
Wynn Legon, Ph.D. (wlegon@vtc.vt.edu)

focused ultrasound
[Image source: Insightec]

The research institute has two Zeiss laser scanning confocal microscopes: the LSM 700 and the LSM 710.

Location: 
Room R1028, 2 Riverside Circle, Roanoke VA

Facility Contacts:
Christie Lacy (christie21@vtc.vt.edu)
Shannon Farris, Ph.D. (farrissl@vt.edu)

zeiss LSM 700

The research institute's large bore MRI facilities include four scanners: two Siemens MAGNETOM Trio 3-Tesla MRIs, and two Siemens MAGNETOM Prisma 3-Tesla MRIs. 

Locations: 

  • Siemens MAGNETOM Trio: Room R1082,  2 Riverside Circle, Roanoke, VA
  • Siemens MAGNETOM Trio: Research Building 26, Virginia Tech Corporate Research Center, Blacksburg, VA
  • Siemens MAGNETOM Prisma: Room R1081, 2 Riverside Circle, Roanoke, VA
  • Siemens MAGNETOM Prisma: Room G404, 4 Riverside Circle, Roanoke, VA

Facility Contacts:
Duy Phan (dqphan@vtc.vt.edu, 540-526-2034)
Read Montague, Ph.D. (read@vtc.vt.edu, 540-526-2006)

Siemens trio MRI

The Bruker BioSpec 94/20 USR Scanner with PET insert allows simultaneous MRI and PET data acquisition.

Location: 
Room G412, 4 Riverside Circle, Roanoke VA

Facility Contacts:
Maosen Wang, Ph.D. (maosen@vtc.vt.edu, 540-526-2371)
Jenny Munson, Ph.D. (munsonj@vt.edu, 540-526-2238)

Bruker BioSpec MRI

The metabolic kitchen features commercial grade cooking facilities, Nutrition Data System for Research access, and a dining and observational area. 

Location: 
Room 2002, 4 Riverside Circle, Roanoke, VA

Facility Contact:
Alexandra DiFeliceantonio, Ph.D. (dife@vt.edu, 540-526-2285)

metabolic kitchen

The Bruker Ultima in vitro Multiphoton Microscope provides simultaneous imaging and electrophysiology.

Location: 
Room R1015, 2 Riverside Circle, Roanoke, VA

Facility Contacts:
Christie Lacy (christie21@vtc.vt.edu)
Shannon Farris, Ph.D. (farrissl@vt.edu)

Multiphoton Microscope
[Image source: Bruker]

The Thermo Fisher Scientific Apreo VolumeScope is a scanning serial block face electron microscope for automated acquisition of large volumes.

Location: 
Room 2306A, 4 Riverside Circle, Roanoke VA

Facility Contacts:
Christie Lacy (christie21@vtc.vt.edu)
Shannon Farris, Ph.D. (farrissl@vt.edu)

Scanning serial block face microscope

The Nikon SoRa Inverted Spinning Disk Confocal Microscope uses multiple pinholes or slits to project a series of 1,000 or more parallel excitation light beams onto the specimen in a multiplexed pattern.

Location: 
Room 1036, 4 Riverside Circle, Roanoke VA

Facility Contacts:
Christie Lacy (christie21@vtc.vt.edu)
Shannon Farris, Ph.D. (farrissl@vt.edu)

Nikon SoRa Spinning Disk Microscope
[Image source: Nikon]

The research institute's Tissue Processing facility provides histology services and instruction to all Fralin Biomedical Research Institute researchers. 

Location: 
Room 2305, 4 Riverside Circle, Roanoke VA

Facility Contacts:
Scott Johnstone, Ph.D. (scottjr@vtc.vt.edu, 540-526-2296)

Leica cryostat

The FEI Tecnai G2 Spirit Twin Transmission Electron Microscope (EM) is a general purpose, high resolution instrument.

Location: 
Room R2029, 2 Riverside Circle, Roanoke VA

Facility Contacts:
Christie Lacy (christie21@vtc.vt.edu)
Shannon Farris, Ph.D. (farrissl@vt.edu)

Transmission Electron Microscope

The respiration calorimeter facility includes one large room (9' x 12') and a smaller flex chamber (4' x 7') in a push-pull configuration to measure metabolic rate and relative substrate utilization of a human study subject.

Location: 
Room 2113, 4 Riverside Circle, Roanoke, VA

Facility Contact:
Charlie Stylianos (kstylian@vt.edu, 540-231-6393)

Whole room calorimeters

Facilities Shared Among FBRI Principal Investigators Only

Please contact the primary faculty member listed below for more information about this equipment. 
 

The Nikon NIE upright confocal microscope is part of the Johnstone Lab and is equipped for in vivo, live cell and fixed stained sample imaging. 

Location: 
Room 2313C, 4 Riverside Circle

Facility Contacts:
Scott Johnstone, Ph.D. (scottrj@vt.edu, 540-526-2296)

Nikon A1R confocal LSM
[Image source: Nikon]

The PerkinElmer IVIS Lumina S5 Imaging System is part of the Lamouille Lab.

Location: 
Room R3246, 2 Riverside Circle

Facility Contacts:
Samy Lamouille, Ph.D. (lamouils@vt.edu, 540-526-2203)

IVIS
[Image source: PerkinElmer]

The mass spectrometry / high-performance liquid chromatography facilities include the Shimadzu - GCMS TQ8050 and the Shimadzu HPLC system - Nexera series, and are part of the Warren Lab. 

*This facility is not yet operational

Location: 
Room 2360B, 4 Riverside Circle

Facility Contacts:
Alexey Zaitsev, Ph.D. (zaitsev@vtc.vt.edu, 540-526-2366)
Junco Warren, Ph.D. (juncowarren@vtc.vt.edu, 540-526-2293)

Shimadzu - GCMS TQ8050

The Seahorse facility for analysis of oxygen rate and proton efflux rate of live cells is part of the LaMantia Lab.

Location: 
Room R2097, 2 Riverside Circle

Facility Contacts:
Daniel Meechan, Ph.D. (meechan@vtc.vt.edu, 540-231-2190)

Seahorse facility
[Image source: Agilent]