Center for Human Neuroscience Research

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CENTER FOR HUMAN
NEUROSCIENCE RESEARCH

About the Center for Human Neuroscience Research

Fralin Biomedical Research Institute scientists in this Center work with volunteer research participants from Roanoke, Blacksburg, and the surrounding communities to understand decision-making, behavior, and brain function and disorders in humans. Researchers in this Center have pioneered new approaches to human neuroimaging, including hyperscanning and magnetoencephalography using optically pumped magnetometry, as well as techniques to record and detect real-time fluctuations in neurochemicals while participants complete decision-making tasks. Led by Read Montague, Ph.D., the Center includes the Computational Psychiatry Unit, Human Neuroimaging Laboratory, and the Human Magnetometry Laboratory.

Neuroeconomics

Connecting neuroscience to economics

Psychology and economics have successfully demonstrated that human behavior is not endlessly variable, but can be captured and quantified by testable laws. Modern neuroscience techniques can identify and link individual differences in decision-making behavior to differences in brain anatomy, brain responses, genetics, and so on. In particular, modern neuroimaging techniques provide the means by which human brain responses can be monitored while subjects are engaged in economic-based behavioral tasks. Our lab has been employing this methodology to study well-quantified group behavioral scenarios in which monetary outcomes vary depending on how people cooperate, compete, or punish others.

The goal of this work is centered on the idea of valuation, especially neural valuation. Valuation is a central concept in economics. In this domain, the value of goods must be put on a common scale in order to compare, contrast, and prioritize their value. In this context, the idea of a currency provides just such a common valuation scale.

Neural valuation and its connection to decision-making

Nervous systems are also equipped with rapid, online valuation systems. These valuation systems equip a mobile creature with a capacity to rank (prioritize) stimuli and internal states. Without valuation systems, a creature would be unable to assess the behavioral value of attending to some stimulus or carrying out some behavior. Rapid valuation is also intimately connected to decision-making mechanisms embedded in nervous systems. Creatures tend to make decisions that lead to more valuable outcomes. From this point of view, it is easy to see that pathologies of valuation will underlie a large number of behavioral abnormalities. These include drug addiction, various forms of mental illness, and even milder developmental behavioral disorders. For example, drug addicts have a serious problem with decision-making algorithms. Otherwise, why would an addict decide to sacrifice biological sustenance in order to put alcohol in their blood or cocaine in their nose? Some of the theoretical frameworks in economics are very useful in uncovering valuation and decision-making mechanisms in the human brain. This is the sense in which Neuroeconomics addresses important, but relatively untested issues related to neural function. Better understanding in this area has broad implications in many fields.

CENTER FOR HUMAN

NEUROSCIENCE RESEARCH FACULTY MEMBER LABS

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Chiu Lab , home
The Chiu Laboratory examines the neuroscience of human motivation and social decision-making.
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King-Casas Lab , home
The King-Casas Lab addresses two broad areas of inquiry: (1) neural underpinnings of valuation and learning in social settings, and (2) how social and economic preferences influence valuation and learning.
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LaConte Lab , home
Research in the LaConte lab is devoted to advanced neuroimaging acquisition and data analysis approaches, aimed at basic scientific discovery as well as understanding and rehabilitating neurological and psychiatric diseases.
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Legon Lab , home
The Legon Lab studies modulation of the human brain via focused ultrasound.
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Montague Lab , home
The Montague Lab's work focuses on computational neuroscience – the connection between physical mechanisms present in real neural tissue and the computational functions that these mechanisms embody.

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The Journal of Neuroscience: Modeling Emotion and Learning of Norms in Social Interactions , redirect
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Daily Mail (UK): Suspicious minds: People have a 'lie detector' in their brains - which lights up when dealing with people we don’t trust , redirect
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ABA Journal: Why some people become temporarily less intelligent in group settings , redirect
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Time: How small groups sap intelligence--especially in women , redirect
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UPCOMING SEMINARS

Presented by the Fralin Biomedical Research Institute and co-hosted by the Center for Human Neuroscience Research

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Virtual Seminar: Electrophysiology of Basal Ganglia and Thalamus in Children Undergoing DBS for Dystonia , home
Dec. 9, 2022, 11:00 a.m. | Terence Sanger, M.D., Ph.D., Professor, Departments of Electrical Engineering, Computer Science, and Pediatric Neurology, University of California - Irvine | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
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In Person Seminar: Prioritizing Individuals and Individual Differences in the Study of Children with Neurodevelopmental Disorders , home
Jan. 27, 2023, 11:00 a.m. | Bradley Schlaggar, M.D., Ph.D., President and Chief Executive Officer, Kennedy Krieger Institute, Johns Hopkins University | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
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In Person Seminar: Functional MRI of Dynamic Physiological States , home
Feb. 24 2023, 11:00 a.m. | Catherine Chang, Ph.D., Assistant Professor, Department of Electrical Engineering and Computer Science, Vanderbilt University | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
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In Person Seminar: Quantifying Diverse Research Representation , home
March 31, 2023, 11:00 a.m. | Jonathan Jackson, Ph.D., Executive Director, Community Access, Recruitment, and Engagement (CARE) Research Center, Harvard University and Massachusetts General Hospital | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research

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CENTER FOR HUMAN
NEUROSCIENCE RESEARCH

About the Center for Human Neuroscience Research

Neuroeconomics

Connecting neuroscience to economics

Neural valuation and its connection to decision-making

CENTER FOR HUMAN

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