Center for Human Neuroscience Research

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CENTER FOR HUMAN
NEUROSCIENCE RESEARCH

About the Center for Human Neuroscience Research

Fralin Biomedical Research Institute scientists in this Center work with volunteer research participants from Roanoke, Blacksburg, and the surrounding communities to understand decision-making, behavior, and brain function and disorders in humans. Researchers in this Center have pioneered new approaches to human neuroimaging, including hyperscanning and magnetoencephalography using optically pumped magnetometry, as well as techniques to record and detect real-time fluctuations in neurochemicals while participants complete decision-making tasks. Led by Read Montague, Ph.D., the Center includes the Computational Psychiatry Unit, Human Neuroimaging Laboratory, and the Human Magnetometry Laboratory.

Neuroeconomics

Connecting neuroscience to economics

Psychology and economics have successfully demonstrated that human behavior is not endlessly variable, but can be captured and quantified by testable laws. Modern neuroscience techniques can identify and link individual differences in decision-making behavior to differences in brain anatomy, brain responses, genetics, and so on. In particular, modern neuroimaging techniques provide the means by which human brain responses can be monitored while subjects are engaged in economic-based behavioral tasks. Our lab has been employing this methodology to study well-quantified group behavioral scenarios in which monetary outcomes vary depending on how people cooperate, compete, or punish others.

The goal of this work is centered on the idea of valuation, especially neural valuation. Valuation is a central concept in economics. In this domain, the value of goods must be put on a common scale in order to compare, contrast, and prioritize their value. In this context, the idea of a currency provides just such a common valuation scale.

Neural valuation and its connection to decision-making

Nervous systems are also equipped with rapid, online valuation systems. These valuation systems equip a mobile creature with a capacity to rank (prioritize) stimuli and internal states. Without valuation systems, a creature would be unable to assess the behavioral value of attending to some stimulus or carrying out some behavior. Rapid valuation is also intimately connected to decision-making mechanisms embedded in nervous systems. Creatures tend to make decisions that lead to more valuable outcomes. From this point of view, it is easy to see that pathologies of valuation will underlie a large number of behavioral abnormalities. These include drug addiction, various forms of mental illness, and even milder developmental behavioral disorders. For example, drug addicts have a serious problem with decision-making algorithms. Otherwise, why would an addict decide to sacrifice biological sustenance in order to put alcohol in their blood or cocaine in their nose? Some of the theoretical frameworks in economics are very useful in uncovering valuation and decision-making mechanisms in the human brain. This is the sense in which Neuroeconomics addresses important, but relatively untested issues related to neural function. Better understanding in this area has broad implications in many fields.

CENTER FOR HUMAN

NEUROSCIENCE RESEARCH FACULTY MEMBER LABS

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Chiu Lab , home
The Chiu Laboratory examines the neuroscience of human motivation and social decision-making.
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King-Casas Lab , home
The King-Casas Lab addresses two broad areas of inquiry: (1) neural underpinnings of valuation and learning in social settings, and (2) how social and economic preferences influence valuation and learning.
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LaConte Lab , home
Research in the LaConte lab is devoted to advanced neuroimaging acquisition and data analysis approaches, aimed at basic scientific discovery as well as understanding and rehabilitating neurological and psychiatric diseases.
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Legon Lab , home
The Legon Lab studies modulation of the human brain via focused ultrasound.
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Montague Lab , home
The Montague Lab's work focuses on computational neuroscience – the connection between physical mechanisms present in real neural tissue and the computational functions that these mechanisms embody.

MEDIA COVERAGE

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Cardinal News: Fralin Institute researcher to speak at Nobel symposium , redirect Date: Sep 08, 2022
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The Roanoke Star: Fralin Biomedical Research Leader to Share Groundbreaking Brain Research at Nobel Symposium , redirect Date: Sep 07, 2022
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Freethink: In a hole in Earth’s magnetic field, neuroscientists are peering into the human brain , redirect Date: Apr 02, 2022
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USA Today: Apps make trading stocks feel like a game, but that may not be a winning investment strategy , redirect Date: Sep 29, 2021

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Augusta Free Press: Advancing addiction, pain research with focused ultrasound , redirect
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Scienmag: Scientists Launch ‘Next Generation’ Human Brain Imaging Lab , redirect
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Radio IQ | WVTF: Human Brain Imaging Project to Study Social Interactions in Real Time , redirect
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WQOW TV: Friends Who Play It Safe May Help Others Make Safer Choices , redirect
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Radio Canada: Video - Our Conspiracy Brain , redirect
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MSN.com: We Are Predisposed to be Conspirators , redirect
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WVII TV: Teens Can Exert Positive Peer Pressure on Friends , redirect
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With Good Reason: The Science of Peer Pressure , redirect
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KETV: Teens Can Influence Peers to Make Safer Decisions , redirect
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KAKE TV: Teen Friends Who Play It Safe May Help Others Make Better Decisions , redirect
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Newswise: Virginia Tech researchers show teens with risk-averse peers make safer choices , redirect
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Freethink: Dopamine and Serotonin May Do More Than We Thought , redirect
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The Scientist: Serotonin and Dopamine Linked to Decision-Making: Study , redirect
Date: Oct 16, 2020
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SciTech Daily: Scientists Find Neurochemicals – Dopamine and Serotonin – Have Unexpectedly Profound Roles in the Human Brain , redirect
Date: Oct 14, 2020
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Technology Networks: Neurochemicals Dopamine and Serotonin Have Unexpected Role in Perception , redirect
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Genetic Engineering and Biotechnology News: Expanded Roles Identified for Dopamine, Serotonin in Human Perception , redirect
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Inverse: 2 Chemicals May Shape Human Perception More Than Previously Thought — Study , redirect
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Medical Xpress: Scientists find neurochemicals have unexpectedly profound roles in the human brain , redirect
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Technology Times: Unexpectedly Neuro-Chemicals Profound Roles In The Human Brain , redirect
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Science Daily: Scientists find neurochemicals have unexpectedly profound roles in the human brain , redirect
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News Medical: Two well-known neurochemicals found to be involved in sub-second perception, cognition , redirect
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Big Lick of Science Podcast: With Dr. Read Montague: Why choose this interview , redirect
Date: May 29, 2020
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Neuroscience for Teenagers: Interview with Read Montague, Ph.D. , redirect
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Science: MRI scanners built for two , redirect
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FreeThink: Diving Deep Into the Brain to Measure Neurotransmitters , redirect
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BYU Radio: Disgust & Decisions on Constant Wonder , redirect
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The Atlantic: Liberals, conservatives act in wildly different ways to repulsive pics , redirect
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The Verge: Meet the Scientists who are Training AI to Diagnose Mental Illness , redirect
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Virginia Business: Virginia Catalyst announces $500,000 for a brain-injury diagnostic method , redirect
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WSLS10: Researchers seek field diagnostic for mild TBI , redirect
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News-Medical: Study provides first ever recording of changing serotonin levels in human brains , redirect
Date: May 03, 2018
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Science Daily: Keep calm and carry on: VTCRI scientists make first serotonin measurements in humans , redirect
Date: Apr 30, 2018
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BrightSurf.com: Keep calm and carry on: VTCRI scientists make first serotonin measurements in humans , redirect
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Augusta Free Press: New study targets effects of social media on collective action , redirect
Date: Mar 16, 2018
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The Naked Scientists: Ant Undertakers and the Human Cell Atlas , redirect
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Science Daily: Scientists find heightened attention to surprise in veterans with PTSD , redirect
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The Roanoke Times: VTCRI research gives family hope , redirect
Date: Feb 13, 2017
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Washington Post: Trump played a clever trick when he called Clinton’s bathroom visit ‘disgusting’ , redirect
Date: Dec 22, 2015
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Times Higher Education: Is industry funding undermining trust in science? , redirect
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PBS: Why buying things makes you happy , redirect
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Forbes: With risky choices, social influence pushes us to greater extremes , redirect
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Science Daily: Extreme sports to hairstyles: Brain study explains risk-taking, fads , redirect
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Medical News Today: Beliefs about nicotine 'may override its effects on the brain' , redirect
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Proceedings of the National Academy of Sciences: Beliefs modulate the effects of drugs on the human brain , redirect
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Observations (Association for Psychological Science): Perspective-Tracking Brain Response Could Help Identify Children with Autism , redirect
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WVTF: Predicting Party Affiliation , redirect
Date: Nov 14, 2014
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Discovery News: Repulsed by Disgusting Images? Must be Republican , redirect
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Huffington Post: How Maggots Can Reveal Whether You’re Liberal or Conservative , redirect
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Newsweek: Liberal or Conservative? How Your Brain Reacts to Disgusting Images Reveals Your Political Affiliation , redirect
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Medical Daily: What's Disgusting? How Your Political Affiliation Ties Into What You Consider Gross , redirect
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Smithsonian: Your Reaction to "Gross" Pictures Can Betray Your Political Beliefs , redirect
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WSET: Researchers Can Predict Whether Liberal or Conservative Using Disgusting Pictures , redirect
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CBS News: How you react to this photo reveals your political beliefs , redirect
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Psych Central: Brain Response to Repulsive Images Predicts Political Affiliation , redirect
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Daily Mail: That’s gross! How your reaction to a single disgusting image can reveal your political leanings - with 98% accuracy , redirect
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Pacific Standard: He's Definitely a Liberal - Just Check Out His Brain Scan , redirect
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Washington Post: Your brain’s response to a gross photo can reveal your political leanings , redirect
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Quartz: Your brain’s response to vile images says a lot about your politics , redirect
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Los Angeles Times: Liberal or conservative? Brain's 'disgust' reaction holds the answer , redirect
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CNBC: Your Brain and the Markets , redirect
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Washington Post: How brain science explains market bubbles and ‘irrational exuberance’ , redirect
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Forbes: People Who Avoid Market Bubbles May Have Brains That Work Differently, Study Says , redirect
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CNBC: Inside the brain of a trader: A biomarker for irrational exuberance , redirect
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WBUR: In Search Of ‘Computational Psychiatry:’ Why Is It A Hot New Field? , redirect
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Forbes: Why Gallup, the WSJ, and Time Are Dead Wrong about Facebook , redirect
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WSLS: Researchers hope to find solutions for teens before risky behavior begins , redirect
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BBC Radio: Personality Politics , redirect
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BBC News: Does brain structure determine your political views? , redirect
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London Evening Standard: How to have a productive meeting at work , redirect
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Psychology Today: Kings and Queens of Chaos , redirect
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Scientific American Mind: The Psychology of Freedom , redirect
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Brisbane Times: Real thing blind-sided, but Pepsi still can't pop its bubble , redirect
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Slate: Sweet Sorrow , redirect
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PR Daily: 10 ways meetings are dumbing us down , redirect
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Virginia Tech Magazine: Quantifying the Adaptable, Sociable, Physical Brain , redirect
Date: Jul 19, 2013
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The Journal of Neuroscience: Modeling Emotion and Learning of Norms in Social Interactions , redirect
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Cognitive Neuroscience Society: From Conditioning Monkeys to Drug Addiction: Understanding Prediction and Reward , redirect
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American Psychological Association's Monitor on Psychology: New research and new ideas , redirect
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Virginia Public Radio: Virginia Conversations: Neuro-Marketing , redirect
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Medical Xpress: Hallmarks of psychiatric illness can reveal themselves remotely , redirect
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TerraDaily: Kirk, Spock together: Putting emotion, logic into computational words , redirect
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Scientific American Mind: VTCRI Assistant Professor Stephen LaConte’s pioneering work on real time fMRI feedback , redirect
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Yahoo! Finance: Here's the real difference between Coke and Pepsi , redirect
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Red Ice Creations: Group settings can diminish expressions of intelligence , redirect
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Trendhunter Tech: Solitude as a social action , redirect
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Impact: Dedicated father mobilizes support for autism research , redirect
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Education Week: Researchers embark on long-term study of brain development , redirect
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TED Blog: Misbehaving Beautifully: Session 6 at TEDGlobal 2012 , redirect
Date: Jun 27, 2012
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TED Blog: Digging deep into the brain: Read Montague at TEDGlobal2012 , redirect
Date: Jun 27, 2012
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Daily Mail (UK): Suspicious minds: People have a 'lie detector' in their brains - which lights up when dealing with people we don’t trust , redirect
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PayScale: Do you experience social anxiety? Research reveals influence of small-group dynamics on perceptions of IQ , redirect
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Education Week: How and why rankings matter: a brain-imaging perspective on teacher evaluation , redirect
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Collegiate Times: Group projects yield less work , redirect
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The Guardian (UK): Warning: meetings may be bad for your IQ , redirect
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The Telegraph (UK): Attending meetings lowers IQ: research , redirect
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Irish Times: How long and boring meetings diminish brainpower , redirect
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Financial Times: Meetings of minds are effectively a tool for dulling them , redirect
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ABA Journal: Why some people become temporarily less intelligent in group settings , redirect
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New York Daily News: Brain drain: how meetings make you dumber , redirect
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Huffington Post: Business meetings are making you dumb? , redirect
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Wall Street Journal: Speaking up is hard to do: researchers explain why , redirect
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Wall Street Journal: Ideas Market Blog: Being ranked can reduce IQ , redirect
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The Washington Post (Wonkblog): Working in groups can lower your intelligence, particularly if you’re a woman , redirect
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Wired.com: Human nature and the neurobiology of conflict , redirect
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Time: How small groups sap intelligence--especially in women , redirect
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Psych Central: IQ drops when you're in a group , redirect
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Everyday Health: Group meetings make you sound stupid , redirect
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The Atlantic: Better doctors focus on mistakes , redirect
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Roanoke Star-Sentinel: Research says experienced doctors are poorest learners , redirect
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BBC News: Exploiting neuroscience lessons to shape policy , redirect
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United Press International: Best doctors learn from mistakes , redirect
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Slate: Using Neuroscience to help addicts kick the habit , redirect
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Medical News Today: Decision-making in action , redirect
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Science Daily: Dopamine release in human brain tracked at microsecond timescale reveals decision-making , redirect
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Wired: The Frontal Cortex: Can We Prevent the Next Bubble? , redirect
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National Academy of Sciences: The Second Raymond and Beverly Sackler U.S.A.-U.K. Scientific Forum: Neuroscience and the Law , redirect
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Business Insider: It's almost NEVER a good idea to change your company's logo , redirect
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Business Wire: Dr. Read Montague, Virginia Tech/UCL Neuroscience Professor, Joins EmSense Science Advisory Board , redirect
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Not Exactly Rocket Science; Discover Magazine: The signature of the bluffing brain , redirect
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New Scientist: Brain scans show more than buyers bargained for , redirect
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nytimes.com: It Costs How Much? My Brain Says Otherwise , redirect
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WDBJ7 TV: Virginia Tech researchers using “next generation” tech to study our brains , redirect
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HealthImaging: New brain imaging lab takes people outside cramped MRIs for face-to-face research , redirect
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Psychreg: Scientists Say Active Early Learning Shapes the Adult Brain , redirect
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24HTECH: Virginia Tech Launches ‘Next Generation’ Human Brain Imaging Lab , redirect
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UPCOMING SEMINARS

Presented by the Fralin Biomedical Research Institute and co-hosted by the Center for Human Neuroscience Research

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In Person Seminar: The Cyclical Nature of Food Reinforcement, Decision-making, and Overeating , home
Oct. 14, 2022, 11:00 a.m. | Kyle S. Burger, Ph.D., MPH, RD, Associate Professor, Department of Nutrition, Gillings School of Public Health, University of North Carolina, Chapel Hill | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
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In Person Seminar: Electrophysiology of Basal Ganglia and Thalamus in Children Undergoing DBS for Dystonia , home
Dec. 9, 2022, 11:00 a.m. | Terence Sanger, M.D., Ph.D., Professor, Departments of Electrical Engineering, Computer Science, and Pediatric Neurology, University of California - Irvine | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
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In Person Seminar: Prioritizing Individuals and Individual Differences in the Study of Children with Neurodevelopmental Disorders , home
Jan. 27, 2023, 11:00 a.m. | Bradley Schlaggar, M.D., Ph.D., President and Chief Executive Officer, Kennedy Krieger Institute, Johns Hopkins University | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
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In Person Seminar: Functional MRI of Dynamic Physiological States , home
Feb. 24 2023, 11:00 a.m. | Catherine Chang, Ph.D., Assistant Professor, Department of Electrical Engineering and Computer Science, Vanderbilt University | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
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In Person Seminar: Quantifying Diverse Research Representation , home
March 31, 2023, 11:00 a.m. | Jonathan Jackson, Ph.D., Executive Director, Community Access, Recruitment, and Engagement (CARE) Research Center, Harvard University and Massachusetts General Hospital | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research

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CENTER FOR HUMAN
NEUROSCIENCE RESEARCH

About the Center for Human Neuroscience Research

Neuroeconomics

Connecting neuroscience to economics

Neural valuation and its connection to decision-making

CENTER FOR HUMAN

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