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In Person Seminar: Engineering Post-translational Regulation of Ion Channels

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Henry M. Colecraft, Ph.D.

John C. Dalton Professor 
Department of Physiology and Cellular Biophysics
Columbia University Irving Medical Center

Pioneers in Biomedical Research Seminar: Engineering Post-translational Regulation of Ion Channels

Date: April 21, 2023

Time: 11 a.m. - 12 p.m.

About this Seminar

Modulation of ion channel expression and activity is a critical mechanism to tune physiology and attack diseases, and also an important avenue for developing novel therapeutics. Dr. Colecraft will discuss our work focused on engineering new ways to selectively modulate the expression and function of distinct ion channels that exploits targeted induced proximity of enzymes including E3 ubiquitin ligases, deubiquitinases, and kinases. The applications of this approach to develop novel therapeutics will be emphasized.     


Additional Details

This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Center for Vascular and Heart Research. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.

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