In Person Seminar: Cytoskeletal Control of Local Protein Synthesis and Directed Cardiac Growth
Benjamin Prosser, Ph.D.
Associate Professor
Physiology
Associate Director, Pennsylvania Muscle Institute
Director, Center for Epilepsy and NeuroDevelopmental Disorders
Perelman School of Medicine
University of Pennsylvania
Pioneers in Biomedical Research Seminar: Cytoskeletal Control of Local Protein Synthesis and Directed Cardiac Growth
Date: Feb. 23, 2024
Time: 11 a.m. - 12 p.m.
Archived video
About this Seminar
In response to stress, adaptive or maladaptive remodeling of heart muscle cells (i.e. cardiomyocyte hypertrophy) helps dictate the resulting structure and performance of the heart. Dr. Prosser and his lab find that upon increased demand, the cardiomyocyte microtubule network orchestrates the subcellular transport and positioning of mRNAs and the translational machinery to control where and when new protein synthesis occurs. Microtubule-based transport thus represents a novel, tunable mechanism to control and bias “local translation” in striated muscle, enabling the directed growth of cardiomyocytes to regulate cardiac form and function.
Additional Details
This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Center for Vascular and Heart Research. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.
You May Also Be Interested In...
-
Home Item
A Human-Centric View of Cerebellar Development , homeApril 18, 2025, 11:00 a.m. | Kathleen Millen, Ph.D., Professor, Department of Pediatrics/Genetics, Associate Director and Principal Investigator, Seattle Children's Hospital Research Institute, The University of Washington School of Medicine | Co-Sponsored by the Center for Neurobiology Research, Fralin Biomedical Research Institute
-
Home Item
Molecular and Neurobiological Studies in Rett Syndrome and Other MECP2 Disorders , homeMay 1, 2025, 5:30 p.m. (Reception at 5 p.m.) | Huda Zoghbi, M.D., Professor, Pediatrics, Molecular and Human Genetics, Neuroscience, and Neurology; Director, Jan and Dan Duncan Neurological Research Institute, Baylor College of Medicine; Member, National Academy of Medicine | Maury Strauss Distinguished Public Lecture
-
Home Item
A Novel Bispecific Antibody to Target the Brain Tumor Microenvironment , homeMay 2, 2025, 11:00 a.m. | Khuson Yun, Ph.D., Associate Professor, Department of Neurology, Houston Methodist Chair, Neurodegenerative Disease Research, Houston Methodist Research Institute, Weill Cornell Medical College | Co-Sponsored by the Fralin Biomedical Research Institute Cancer Research Center – Roanoke
-
Home Item
Transformation of Information from the External World by Cortical Circuits During Learning , homeMay 9, 2025, 11:00 a.m. | Alison Barth, Ph.D., Professor, Department of Biological Sciences, Carnegie Mellon University | Co-Sponsored by the Center for Neurobiology Research, Fralin Biomedical Research Institute
-
Home Item
The Role of Exercise in Memory Function , homeMay 23, 2025, 11:00 a.m. | Henriette van Praag, Ph.D., Associate Professor, Department of Biomedical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University | Co-Sponsored by the Center for Exercise Medicine Research, Fralin Biomedical Research Institute
-
Home Item
Pathways and Regulation of Cardiac Nav1.5 Channel Trafficking in Adult Myocytes , homeMay 30, 2025, 11:00 a.m. | Gea-Ny Tseng, Ph.D., Professor, Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine | Co-Sponsored by the Fralin Biomedical Research Institute Center for Vascular and Heart Research