Archived Seminar: Neurovascular Interactions: Mechanisms, Imaging, Therapeutics
Pioneers in Biomedical Research Seminar presented by the Fralin Biomedical Research Institute at VTC
Neurovascular Interactions: Mechanisms, Imaging, Therapeutics
Date: Oct. 30, 2020
Time: 11:00 a.m. - 12:00 p.m.
Virtual Access: Virginia Tech and Carilion Clinic faculty, staff, and students will be sent an email with Zoom login credentials. Participants may also watch the lecture via YouTube livestream on our Live Webcast page.
About This Seminar
The communication between the brain, immune and vascular systems is a key contributor to the onset and progression of neurological diseases. Dr. Akassoglou’s research has uncovered the blood clotting factor fibrinogen as a driver of neuroinflammation, as common thread in a wide range of neurologic diseases, such as multiple sclerosis, Alzheimer’s disease and neurodegenerative diseases. Her lab developed cutting-edge imaging tools to study the neurovascular interface and discovered a role for fibrin in microglia-mediated oxidative stress-dependent spine elimination and novel fibrin-targeting immunotherapy to protect the brain from pathogenic neuroinflammation. Recent advances in functional single-cell transcriptional profiling of neurotoxic innate immunity (Tox-Seq) allowed the development of the oxidative stress cell atlas at the neurovascular interface. These findings could be a common thread for the understanding of the etiology, mechanisms of progression, and the development of new treatments for neurologic diseases with neuroimmune and cerebrovascular dysfunction.
This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Center for Neurobiology Research and the Center for Glial Biology in Health, Disease, and Cancer. The Fralin Biomedical Research Institute Pioneers in Biomedical Research Program offers the expertise of a range of scientists who are exploring frontiers in biomedical research. These seminars are open to Virginia Tech and Carilion Clinic faculty, students, and staff.
You May Also Be Interested In...
Home ItemIn Person Seminar: Win to Fight and Lose to Flight: Innate Yet Flexible Aggression Circuit , home
March 24, 2023, 11 a.m. | Dayu Lin, Ph.D., Professor, Department of Psychiatry, Grossman School of Medicine, New York University | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Neurobiology Research
Home ItemSeminar: Signaling and Metabolic Control of Nucleotide Metabolism in Cancer , home
March 27, 2023, 11 a.m. | Eunus S. Ali, Ph.D., Postdoctoral Associate, Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University | Seminar
Home ItemIn Person Seminar: Quantifying Diverse Research Representation , home
March 31, 2023, 11:00 a.m. | Jonathan Jackson, Ph.D., Executive Director, Community Access, Recruitment, and Engagement (CARE) Research Center, Harvard University and Massachusetts General Hospital | Pioneers in Biomedical Research Seminar Series | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
Home ItemIn Person Lecture: Synaptic Injury: A Link to the Past , home
March 31, 2023, 1 p.m. | Terrance Kummer, M.D., Ph.D., Associate Professor of Neurology, Washington University School of Medicine in St. Louis | Timothy A. Johnson Medical Scholar Lecture Series
Home ItemSeminar: Understanding Cancer: From Development to Therapy , home
April 5, 2023, 11 a.m. | Biplab Dasgupta, M.S., Ph.D., MBA, Professor of Pediatrics, Division of Oncology, Cincinnati Children's Hospital | Seminar
Katerina Akassoglou, Ph.D.
Senior Investigator at the Gladstone Institutes; and a Professor in the Department of Neurology at the University of California San Francisco