Led by principal investigator Anthony-Samuel LaMantia, Ph.D., the LaMantia Lab focuses on the developmental mechanisms that build neural circuits for distinct behaviors. The laboratory addresses these issues via genetic, molecular and cell biological analyses as well as assessments of neural circuit function and related behaviors. One essential aspect Dr. LaMantia's work integrates genetic and cellular mechanisms underlying neural development with those for cardiovascular and craniofacial development—the coordinated construction of brains, hearts, and faces. Dr. LaMantia's goal is to use insights into basic development and genetics to address the causes and help develop new diagnostic and therapeutic approaches for the broad range of developmental disorders that compromise the brain as well as other organ systems. These disorders result in a lifetime of health challenges for the affected infants and children, as well as for their families and caregivers.