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May 30, 2025

Virginia Tech researchers find promise in a new peptide drug to combat a deadly brain cancer

A lab-designed molecule developed and extensively studied by scientists with Virginia Tech’s Fralin Biomedical Research Institute at VTC could represent a breakthrough in slowing tumor recurrence in glioblastoma, an aggressive and deadly form of brain cancer.

In a study published May 16 in Cell Death and Disease, researchers identified a previously unknown trait of cancer cells that shows promise for therapeutic intervention. The group outlined the mechanism of action and effectiveness of the experimental drug known as JM2, revealing its potential as a peptide therapy to target cancer cells that can renew and regrow, even after chemotherapy and radiation.

Glioblastoma, the most common form of malignant brain tumor, is particularly difficult to treat. The median survival after diagnosis is just over 14 months. 

 

Campus News

Creating a healthier future. For everyone.

The Fralin Biomedical Research Institute at VTC is one of the nation’s fastest-growing academic biomedical research enterprises and a destination for world-class researchers. The institute’s Virginia Tech scientists focus on diseases that are the leading causes of death and suffering in the United States, including brain disorders, heart disease, and cancer. Since its founding in 2010, the research institute has experienced unprecedented growth: doubling its enterprise and lab facilities in Roanoke, while also investing in brand-new laboratories on the Children’s National Research & Innovation Campus in Washington, D.C.

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Giving to the Research Institute

Your generous support of the Fralin Biomedical Research Institute's rigorous biomedical research enterprise makes a difference for our faculty, students, and patients. Every donation helps accelerate the pace of new discoveries to help patients with cancer, neurological disorders, heart disease, and even rare genetic disorders. Private donations fast-track our progress.