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Dr. Poelzing's Publications

For a more complete list of publications, visit the following publication sites: PubMed

Warren M, Poelzing S. The Calcium Transient Coupled to the L-Type Calcium Current Attenuates Action Potential Alternans. bioRxiv [Preprint]. 2023 Apr 28:2023.04.25.538350. doi: 10.1101/2023.04.25.538350. PMID: 37163125; PMCID: PMC10168326.

Zhang Y, Wu X, Vadlamani RA, Lim Y, Kim J, David K, Gilbert E, Li Y, Wang R, Jiang S, Wang A, Sontheimer H, English D, Emori S, Davalos RV, Poelzing S, Jia X. Multifunctional ferromagnetic fiber robots for navigation, sensing, and treatment in minimally invasive surgery. bioRxiv [Preprint]. 2023 Jan 30:2023.01.27.525973. doi: 10.1101/2023.01.27.525973. PMID: 36778450; PMCID: PMC9915472.

Ripplinger CM, Glukhov AV, Kay MW, Boukens BJ, Chiamvimonvat N, Delisle BP, Fabritz L, Hund TJ, Knollmann BC, Li N, Murray KT, Poelzing S, Quinn TA, Remme CA, Rentschler SL, Rose RA, Posnack NG. Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals. Am J Physiol Heart Circ Physiol. 2022 Dec 1;323(6):H1137-H1166. doi: 10.1152/ajpheart.00439.2022. Epub 2022 Oct 21. PMID: 36269644; PMCID: PMC9678409.

Binder MS, Wu Y, Baker JW, Rowe JF, Wyatt DA, Choate C, Poelzing S, Joseph M. A retrospective comparison of albumin versus mannitol priming fluid with relation to postoperative atrial fibrillation. J Card Surg. 2022 Nov;37(11):3485-3491. doi: 10.1111/jocs.16960. Epub 2022 Sep 18. PMID: 36116062; PMCID: PMC9826347.

King DR, Hardin KM, Hoeker GS, Poelzing S. Re-evaluating methods reporting practices to improve reproducibility: an analysis of methodological rigor for the Langendorff whole-heart technique. Am J Physiol Heart Circ Physiol. 2022 Jun 24. doi: 10.1152/ajpheart.00164.2022. Epub ahead of print. PMID: 35749719.

Qian SS, Crandell I, Hanlon A, Joseph M, Poelzing S. Predictive Capability of Metabolic Panels for Postoperative Atrial Fibrillation in Cardiac Surgery Patients. J Surg Res. 2022 May 26;278:271-281. doi: 10.1016/j.jss.2022.04.061. Epub ahead of print. PMID: 35636203.

Lin J, Abraham A, George SA, Greer-Short A, Blair GA, Moreno A, Alber BR, Kay MW, Poelzing S. Ephaptic Coupling Is a Mechanism of Conduction Reserve During Reduced Gap Junction Coupling. Front Physiol. 2022 May 5;13:848019. doi: 10.3389/fphys.2022.848019. PMID: 35600295; PMCID: PMC9117633.

Morningstar JE, Gensemer C, Moore R, Fulmer D, Beck TC, Wang C, Moore K, Guo L, Sieg F, Nagata Y, Bertrand P, Spampinato RA, Glover J, Poelzing S, Gourdie RG, Watts K, Richardson WJ, Levine RA, Borger MA, Norris RA. Mitral Valve Prolapse Induces Regionalized Myocardial Fibrosis. J Am Heart Assoc. 2021 Dec 21;10(24):e022332. doi: 10.1161/JAHA.121.022332. Epub 2021 Dec 7. PMID: 34873924.

Wu X, Hoeker GS, Blair GA, King DR, Gourdie RG, Weinberg SH, Poelzing S. Hypernatremia and intercalated disc edema synergistically exacerbate long-QT syndrome type 3 phenotype. Am J Physiol Heart Circ Physiol. 2021 Dec 1;321(6):H1042-H1055. doi: 10.1152/ajpheart.00366.2021. Epub 2021 Oct 8. PMID: 34623182.

King DR, Entz M 2nd, Blair GA, Crandell I, Hanlon AL, Lin J, Hoeker GS, Poelzing S. The conduction velocity-potassium relationship in the heart is modulated by sodium and calcium. Pflugers Arch. 2021 Mar;473(3):557-571. doi: 10.1007/s00424-021-02537-y. Epub 2021 Mar 4. PMID: 33660028; PMCID: PMC7940307.

Hoeker GS, James CC, Tegge AN, Gourdie RG, Smyth JW, Poelzing S. Attenuating loss of cardiac conduction during no-flow ischemia through changes in perfusate sodium and calcium. Am J Physiol Heart Circ Physiol. 2020 Aug 1;319(2):H396-H409. doi: 10.1152/ajpheart.00112.2020. Epub 2020 Jul 17. PMID: 32678707; PMCID: PMC7473923.

Nowak MB, Poelzing S, Weinberg SH. Mechanisms underlying age-associated manifestation of cardiac sodium channel gain-of-function. J Mol Cell Cardiol. 2020 Dec 26;153:60-71. doi: 10.1016/j.yjmcc.2020.12.008. [Epub ahead of print] PubMed PMID: 33373643; NIHMSID:NIHMS1659961.

King DR, Padget RL, Perry J, Hoeker G, Smyth JW, Brown DA, Poelzing S. Elevated perfusate [Na+] increases contractile dysfunction during ischemia and reperfusion. Sci Rep. 2020 Oct 14;10(1):17289. doi: 10.1038/s41598-020-74069-x. PMID: 33057157; PMCID: PMC7560862.

Allen ME, Pennington ER, Perry JB, Dadoo S, Makrecka-Kuka M, Dambrova M, Moukdar F, Patel HD, Han X, Kidd GK, Benson EK, Raisch TB, Poelzing S, Brown DA, Shaikh SR. The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats. Commun Biol. 2020 Jul 17;3(1):389. doi: 10.1038/s42003-020-1101-3. PMID: 32680996; PMCID: PMC7368046.

Nowak MB, Greer-Short A, Wan X, Wu X, Deschênes I, Weinberg SH, Poelzing S. Intercellular Sodium Regulates Repolarization in Cardiac Tissue with Sodium Channel Gain of Function. Biophys J. 2020 Jun 2;118(11):2829-2843. doi: 10.1016/j.bpj.2020.04.014. Epub 2020 Apr 21. PubMed PMID: 32402243; PubMed Central PMCID: PMC7264809.

Schultz F, Swiatlowska P, Alvarez-Laviada A, Sanchez-Alonso JL, Song Q, de Vries AAF, Pijnappels DA, Ongstad E, Braga VMM, Entcheva E, Gourdie RG, Miragoli M, Gorelik J. Cardiomyocyte-myofibroblast contact dynamism is modulated by connexin-43. FASEB J. 2019 Sep;33(9):10453-10468. doi: 10.1096/fj.201802740RR. Epub 2019 Jul 5. PubMed PMID: 31253057; PubMed Central PMCID: PMC6704460.

Jiang J, Hoagland D, Palatinus JA, He H, Iyyathurai J, Jourdan LJ, Bultynck G, Wang Z, Zhang Z, Schey K, Poelzing S, McGowan FX, Gourdie RG. Interaction of α Carboxyl Terminus 1 Peptide With the Connexin 43 Carboxyl Terminus Preserves Left Ventricular Function After Ischemia-Reperfusion Injury. J Am Heart Assoc. 2019 Aug 20;8(16):e012385. doi: 10.1161/JAHA.119.012385. Epub 2019 Aug 19. PubMed PMID: 31422747; PubMed Central PMCID: PMC6759879.

George SA, Hoeker G, Calhoun PJ, Entz M 2nd, Raisch TB, King DR, Khan M, Baker C, Gourdie RG, Smyth JW, Nielsen MS, Poelzing S. Modulating cardiac conduction during metabolic ischemia with perfusate sodium and calcium in guinea pig hearts. Am J Physiol Heart Circ Physiol. 2019 Apr 1;316(4):H849-H861. doi: 10.1152/ajpheart.00083.2018. Epub 2019 Feb 1. PubMed PMID: 30707595; PubMed Central PMCID: PMC6483020.

Raisch T, Khan M, Poelzing S. Quantifying Intermembrane Distances with Serial Image Dilations. J Vis Exp. 2018 Sep 28;(139). doi: 10.3791/58311. PubMed PMID: 30320747; PubMed Central PMCID: PMC6235350.

Kinney N, Larsen TR, Kim DM, Varghese RT, Poelzing S, Garner HR, AlMahameed ST. Whole-exome sequencing reveals microsatellite DNA markers for response to dofetilide initiation in patients with persistent atrial fibrillation: A pilot study. Clin Cardiol. 2018 Jun;41(6):849-854. doi: 10.1002/clc.22969. Epub 2018 Jun 11. PubMed PMID: 29671888; PubMed Central PMCID: PMC6489891.

Raisch TB, Yanoff MS, Larsen TR, Farooqui MA, King DR, Veeraraghavan R, Gourdie RG, Baker JW, Arnold WS, AlMahameed ST, Poelzing S. Intercalated Disk Extracellular Nanodomain Expansion in Patients With Atrial Fibrillation. Front Physiol. 2018;9:398. doi: 10.3389/fphys.2018.00398. eCollection 2018. PubMed PMID: 29780324; PubMed Central PMCID: PMC5945828.

Entz M 2nd, King DR, Poelzing S. Design and validation of a tissue bath 3-D printed with PLA for optically mapping suspended whole heart preparations. Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1190-H1198. doi: 10.1152/ajpheart.00150.2017. Epub 2017 Sep 22. PubMed PMID: 28939646; PubMed Central PMCID: PMC5814657.

George SA, Calhoun PJ, Gourdie RG, Smyth JW, Poelzing S. TNFα Modulates Cardiac Conduction by Altering Electrical Coupling between Myocytes. Front Physiol. 2017;8:334. doi: 10.3389/fphys.2017.00334. eCollection 2017. PubMed PMID: 28588504; PubMed Central PMCID: PMC5440594.

Greer-Short A, George SA, Poelzing S, Weinberg SH. Revealing the Concealed Nature of Long-QT Type 3 Syndrome. Circ Arrhythm Electrophysiol. 2017 Feb;10(2):e004400. doi: 10.1161/CIRCEP.116.004400. PubMed PMID: 28213505; PubMed Central PMCID: PMC5319726.

Hoeker GS, Skarsfeldt MA, Jespersen T, Poelzing S. Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts. Physiol Rep. 2017 Jan;5(1). doi: 10.14814/phy2.13120. Epub 2017 Jan 13. PubMed PMID: 28087819; PubMed Central PMCID: PMC5256165.

Abdullah OM, Gomez AD, Merchant S, Heidinger M, Poelzing S, Hsu EW. Orientation dependence of microcirculation-induced diffusion signal in anisotropic tissues. Magn Reson Med. 2016 Oct;76(4):1252-62. doi: 10.1002/mrm.25980. Epub 2015 Oct 29. PubMed PMID: 26511215; PubMed Central PMCID: PMC5648001.

Veeraraghavan R, Lin J, Keener JP, Gourdie RG, Poelzing S. (2016). Potassium Channels in the Cx43 Gap Junction Perinexus Modulate Ephaptic Coupling: An Experimental and Modeling Study. Pflugers Archiv.

Abdullah OM, Gomez AD, Merchant S, Heidinger M, Poelzing S, Hsu EW. (2015). Orientation dependence of microcirculation-induced diffusion signal in anisotropic tissues. Magnetic Resonance in Medicine.

Veeraraghavan R, Lin J, Hoeker GS, Keener JP*, Gourdie RG*, Poelzing S*. (2015). Sodium channels in the Cx43 gap junction perinexus may constitute a cardiac ephapse: an experimental and modeling study. Pflugers Archive - European Journal of Physiology.

Greer-Short A, Poelzing S. (2015). Temporal response of ectopic activity in guinea pig ventricular myocardium in response to isoproterenol and acetylcholine. Frontiers in Physiology 6.

Varano AC, Rahimi A, Dukes MJ, Poelzing S, McDonald SM, Kelly DF. (2015). Visualizing virus particle mobility in liquid at the nanoscale. Chemical Communications 2: 1-6.

Radwański PB, Brunello L, Veeraraghavan R, Ho H, Lou Q, Makara MA, Belevych AE, Anghelescu M, Priori SG, Volpe P, Hund TJ, Janssen PM, Mohler PJ, Bridge JH, Poelzing S, Györke S. (2014). Neuronal Na+ Channel Blockade Suppresses Arrhythmogenic Diastolic Ca2+ Release. Cardiovascular Research.

Veeraraghavan R, Poelzing S, Gourdie RG. (2014). Novel ligands for zipping and unzipping the intercalated disk: today's experimental tools, tomorrow's therapies? Cardiovasc Res 104(2): 229-30.

Veeraraghavan R, Poelzing S, Gourdie RG. (2014). Intercellular electrical communication in the heart: a new, active role for the intercalated disk. Cell Commun Adhes.

Veeraraghavan R, Gourdie RG, Poelzing S. (2014). Mechanisms of Cardiac Conduction: A History of Revisions. Am J Physiol Heart Circ Physiol 306(5): H619-27.

Veeraraghavan R, Poelzing S, Gourdie RG. (2014). Old Cogs, New Tricks: A Scaffolding Role For Connexin43 And A Junctional Role For Sodium Channels?. FEBS Lett.

Rhett JM, Veeraraghavahan S, Poelzing S, Gourdie RG. (2013). The perinexus: Sign-post on the path to a new model of cardiac conduction? Trends in Cardiovascular Medicine.

Radwański PB, Greer-Short A, Poelzing S. (2013). Inhibition of Na+ channels ameliorates arrhythmias in a drug-induced model of Andersen-Tawil syndrome. Heart Rhythm 10(2): 255-63.

Veeraraghavan R, Larsen AP, Torres N, Grunnet M, Poelzing S. (2012). Potassium channel activators differentially modulate the effect of sodium channel blockade on cardiac conduction. Acta Physiologica.

Larsen AP, Sciuto KJ, Moreno AP, Poelzing S. (2012). The voltage sensitive dye di-4-ANEPPS slows conduction velocity in isolated guinea pig hearts. Heart Rhythm Journal 9(9): 1493-500.

Rigby JR, Poelzing S. (2011). A novel frequency analysis method for assessing K(ir)2.1 and Na (v)1.5 currents. Ann Biomed Eng 40(4): 946-54.

Veeraraghavan R, Salama ME, Poelzing S. (2011). Interstitial volume modulates the conduction velocity- gap junction relationship. Am J Physiolo Heart Circ Physiol.

Radwanski P, Poelzing S. (2011). NCX is an important determinant for premature ventricular activity in a drug induced model of Andersen-Tawil syndrome. Cardiovasc Res 92(1): 57-66.

Rigby JR, Poelzing S. (2011). Recapitulation of an ion channel current IV curve using frequency components. J Vis Exp 48: 2361.

Shinlapawittayatorn K, Dudash LA, Du XX, Heller L, Poelzing S, Ficker E, Deschenes I. (2011). A novel strategy using cardiac sodium channel polymorphic fragments to rescue trafficking deficient SCN5A mutations. Circ Genetics 4(5): 500-9.

Radwanski P, Veeraraghavan R, Poelzing S. (2010). Cytosolic calcium accumulation underlies ventricular arrhythmias in guinea pig model of Andersen-Tawil syndrome. Heart Rhythm 7(10): 1428-35.

Larsen AP, Grunnet M, Olesen SP, Poelzing S. (2010). Pharmacological activation of IKr impairs conduction in guinea pig hearts. J Cardiovasc Electrophysiol 21(8): 923-9.

Strom M, Wan X, Poelzing S, Ficker E, Rosenbaum DS. (2009). Gap junction heterogeneity as mechanism for electrophysiologically distinct properties across the ventricular wall. Am J Physiol Heart Circ Physiol 298(3): H787-94.

Poelzing S, Smoot A, Veeraraghavan R. (2008). Novel x-ray attenuation mechanism: role of inter-atomic distance. Med Phys 35(10): 4386-95.

Veeraraghavan R, Poelzing S. (2008). Mechanisms underlying increased right ventricular conduction sensitivity to flecainide challenge. Cardiovasc. Res 77(4): 749-56.

Poelzing S, Veeraraghavan R. (2007). Heterogeneous ventricular Cchamber response to hypokalemia and inwardrectifier potassium channel blockade underlies bifurcated T-wave in guinea pig. Am J Physiol Heart Circ Physiol 292(6): H3043-51.

Poelzing S, Veeraraghavan R. (2007). Heterogeneous ventricular Cchamber response to hypokalemia and inwardrectifier potassium channel blockade underlies bifurcated T-wave in guinea pig. Am J Physiol Heart Circ Physiol 292(6): H3043-51.