Dr. Smyth's Publications
For a more complete list of publications, visit the following publication sites: PubMed
James CC, Zeitz MJ, Calhoun PJ, Lamouille S, Smyth JW. (2018). Altered translation initiation of Gja1 limits gap junction formation during epithelial-mesenchymal transition. Molecular Biology of the Cell 29(7): 773-880.
Smyth JW, Zhang SS, Sanchez JM, Lamouille S, Vogan JM, Hesketh GG, Hong T, Tomaselli GF, Shaw RM. (2014). A 14-3-3 mode-1 binding motif initiates gap junction internalization during acute cardiac ischemia. Traffic 15(6): 684-699.
Smyth JW, Shaw RM. (2013). Autoregulation of connexin43 gap junction formation by internally translated isoforms. Cell Reports.
Hong TT, Smyth JW, Chu KY, Vogan JM, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, Hoopes CW, Ocorr K, Chi NC, Shaw RM. (2012). BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes. Heart Rhythm 9(5).
Horiuchi D, Kusdra L, Huskey NE, Chandriani S, Lenburg ME, Gonzalez-Angulo AM, Creasman KJ, Bazarov AV, Smyth JW, Davis SE, Yaswen P, Mills GB, Esserman LJ, Goga A. (2012). MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition. The Journal of Experimental Medicine 209(4): 679-96.
Smyth JW, Vogan JM, Buch PJ, Zhang SS, Fong TS, Hong TT, Shaw RM. (2012). Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane. Circulation Research 110(7).
Smyth JW, Shaw RM. (2012). The gap junction life cycle. Heart Rhythm 9(1): 151-3.
Lamouille S, Connonlly E, Smyth JW, Akhurst RJ, Derynck R. (2012). TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion. Journal of Cell Science 125: 1259-73.
Smyth JW, Shaw RM. (2012). Visualizing cardiac ion channel trafficking pathways. Methods in Enzymology 505: 187-202.
Zhang SS, Kim KH, Rosen A, Smyth JW, Sakuma R...Shaw RM, Hui CC, Bruneau BG, Backx PH. (2011). Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network. Proceedings of the National Academy of Sciences 108(33): 13576-81.
Nordstrom SM, Holliday BA, Sos BC, Smyth JW, Levy RE, Dukes JW, Lord ST, Weiss EJ. (2010). Increased thrombosis susceptibility and altered fibrin formation in STAT5-deficient mice. Blood 116(25): 5724-33.
Smyth JW, Shaw RM. (2010). Forward trafficking of ion channels: what the clinician needs to know. Heart Rhythm 7(8).
Smyth JW, Hong TTH, Gao D, Vogan J, Jensen B, Fong T, Simpson P, Stainier D, Chi N, Shaw RM. (2010). Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. The Journal of Clinical Investigation 120(1): 87-9.
Saxena A, Fish JE, White MD, Yu S, Smyth JW, Shaw RM, DiMaio JM, Srivastava D. (2008). Stromal cell-derived factor-1α is cardioprotective after myocardial infarction. Circulation 117: 2224-2231.
Smyth JW, Shaw RM. (2008). Visualizing ion channel dynamics at the plasma membrane. Heart Rhythm 5: S7-11.
. (2005). Treatment of rapidly growing K-BALB and CT26 mouse tumors using Semliki Forest virus and its derived vector. Gene Therapy 12(2): 147-59.
Atkins GJ, Smyth JW, Fleeton MN, Galbraith SE, Sheahan BJ. (2004). Alphaviruses and their derived vectors as anti-tumor agents. Current Cancer Drug Targets 4(7): 597-607.