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Dr. Swanger's Publications

For a more complete list of publications, visit the following publication sites: PubMed

Perszyk RE, Swanger SA, Shelley C, Khatri A, Fernandez-Cuervo G, Epplin MP, Zhang J, Le P, Bülow P, Garnier-Amblard E, Gangireddy PKR, Bassell GJ, Yuan H, Menaldino DS, Liotta DC, Liebeskind LS, Traynelis SF. Biased modulators of NMDA receptors control channel opening and ion selectivity. Nat Chem Biol. 2020 Feb;16(2):188-196. doi: 10.1038/s41589-019-0449-5. Epub 2020 Jan 20. PMID: 31959964; PMCID: PMC6986806.

Li J, Zhang J, Tang W, Mizu RK, Kusumoto H, XiangWei W, Xu Y, Chen W, Amin JB, Hu C, Kannan V, Keller SR, Wilcox WR, Lemke JR, Myers SJ, Swanger SA, Wollmuth LP, Petrovski S, Traynelis SF, Yuan H. De novo GRIN variants in NMDA receptor M2 channel pore-forming loop are associated with neurological diseases. Hum Mutat. 2019 Dec;40(12):2393-2413. doi: 10.1002/humu.23895. Epub 2019 Sep 10. PMID: 31429998; PMCID: PMC6874887.

Hanson E, Armbruster M, Lau LA, Sommer ME, Klaft ZJ, Swanger SA, Traynelis SF, Moss SJ, Noubary F, Chadchankar J, Dulla CG. Tonic Activation of GluN2C/GluN2D-Containing NMDA Receptors by Ambient Glutamate Facilitates Cortical Interneuron Maturation. J Neurosci. 2019 May 8;39(19):3611-3626. doi: 10.1523/JNEUROSCI.1392-18.2019. Epub 2019 Mar 7. PMID: 30846615; PMCID: PMC6510335.

Swanger SA, Traynelis SF. Synaptic Receptor Diversity Revealed Across Space and Time. Trends Neurosci. 2018 Aug;41(8):486-488. doi: 10.1016/j.tins.2018.06.001. PMID: 30053950.

Bhattacharya S, Khatri A, Swanger SA, DiRaddo JO, Yi F, Hansen KB, Yuan H, Traynelis SF. Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells. Neuron. 2018 Jul 25;99(2):315-328.e5. doi: 10.1016/j.neuron.2018.06.010. Epub 2018 Jun 28. PMID: 30056832; PMCID: PMC6090556.

Fry AE, Fawcett KA, Zelnik N, Yuan H, Thompson BAN, Shemer-Meiri L, Cushion TD, Mugalaasi H, Sims D, Stoodley N, Chung SK, Rees MI, Patel CV, Brueton LA, Layet V, Giuliano F, Kerr MP, Banne E, Meiner V, Lerman-Sagie T, Helbig KL, Kofman LH, Knight KM, Chen W, Kannan V, Hu C, Kusumoto H, Zhang J, Swanger SA, Shaulsky GH, Mirzaa GM, Muir AM, Mefford HC, Dobyns WB, Mackenzie AB, Mullins JGL, Lemke JR, Bahi-Buisson N, Traynelis SF, Iago HF, Pilz DT. De novo mutations in GRIN1 cause extensive bilateral polymicrogyria. Brain. 2018 Mar 1;141(3):698-712. doi: 10.1093/brain/awx358. PMID: 29365063; PMCID: PMC5837214.

Swanger SA, Vance KM, Acker TM, Zimmerman SS, DiRaddo JO, Myers SJ, Mosley CA, Summer SL, Menaldino DF, Liotta DC, Traynelis SF. (2018). A novel negative allosteric modulator selective for GluN2C/2D-containing NMDARs inhibits synaptic transmission in hippocampal interneurons. ACS Chemical Neuroscience 9(2): 306-19.

Fry AE, Fawcett KA, Zelnik N, Yuan H, Thompson BAN, Shemer-Meiri L, Cushion TD, Mugalaasi H, Sims D, Stoodley N, Chung SK, Rees MI, Patel CV, Brueton LA, Layet V, Giuliano F, Kerr MP, Banne E, Meiner V, Lerman-Sagie T, Helbig KL, Kofman LH, Knight KM. (2018). De novo mutations in GRIN1 cause extensive bilateral polymicrogyria. Brain.

Bhattacharya S, Khatri A, Swanger SA, DiRaddo JO, Yi F, Hansen KB, Yuan H, Traynelis SF. (2018). Triheteromeric GluN1/GluN2A/GluN2C NMDA receptors with unique single channel properties are expressed in cerebellar granule cells. Neuron: In press.

Ogden KK, Chen W, Swanger SA, McDaniel MJ, Hu C, Tankovic A, Kusumoto H, Kosobucki GJ, Schulien AJ, Su J, Pecha J, Bhattacharya S, Aizenman E, Traynelis SF, Yuan H. (2017). Disease-associated mutations implicate the pre-M1 region of NMDA receptors in channel gating. PLOS Genetics 13(1).

Chen W, Shieh C, Swanger SA, Tankovic A, Graham J, Madan-Khetarpal S, Tagliati M, Au M, McGuire M, Wilcox W, Traynelis SF, Yuan H, Pierson TM. (2017). GRIN1 mutation associated with intellectual disability alters NMDA receptor expression and function. Journal of Human Genetics 62(6): 589-97.

Swanger SA, Chen W, Wells G, Burger PB, Tankovic A, Bhattacharya S, Strong KL, Hu C, Kusumoto H, Zhang J, Adams DR, Millichap JJ, Traynelis SF, Yuan H. (2016). American Journal of Human Genetics.

Keen JR, Swanger SA, Traynelis SF, Olson JJ. (2016). The role of glutamate transport and SLC7A11 expression in tumor-associate seizures and survival in patients with malignant gliomas. Annals of Translational Medicine.

Gyoneva S, Swanger SA, Zhang J, Weinshenker D, Traynelis SF. (2016). Altered motility of plaque associated microglia in a model of Alzheimer’s disease. Neuroscience.

Swanger SA, Mattheyses AL, Gentry EG, Herskowitz JH. (2016). ROCK1 and ROCK2 inhibition alters dendritic spine morphology in hippocampal neurons. Cellular Logistics 5(4).

Swanger SA, Vance KM, Pare JF, Sotty F, Fog K, Smith Y, Traynelis SF. (2015). NMDA receptors containing the GluN2D subunit control neuronal function in the subthalamic nucleus. Journal of Neuroscience 35(48): 15971-83.

Yuan H, Myers SJ, Wells G, Nicholson KL, Swanger SA, Lyuboslavsky P, Tahirovic YA, Menaldino DS, Ganesh T, Liotta DC, Snyder JP, Traynelis S. (2015). Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects. Neuron 85(6).