Hong-Jian "James" Wei, Ph.D.
- Wu Lab
Dr. Wei is a cancer biologist with expertise in tumor biology, cancer microenvironment research, and the development of innovative cancer treatments. His current research focuses on central nervous system (CNS) malignancies, with a particular emphasis on diffuse midline glioma (DMG)/diffuse intrinsic pontine glioma (DIPG) and glioblastoma. A significant challenge in treating these malignancies is the heterogeneous blood-brain barrier (BBB), which restricts the efficacy of systemic therapies. Dr. Wei is investigating the use of focused ultrasound (FUS), a non-invasive technique to open the BBB, to enhance drug delivery and immune modulation. This approach is being studied in combination with radiotherapy to improve treatment outcomes for patients with DIPG/DMG and glioblastoma.
- Associate Research Scientist, Department of Radiation Oncology, Columbia University Medical Center
- Core Manager, Small Animal Radiation Research Platform (SARRP), Herbert Irving Comprehensive Cancer Center (HICCC), Columbia University Medical Center
- Translational Research Lead, Initiative for Drug Delivery Innovation
- Project Assistant Professor, School of Dental Technology, College of Oral Medicine, Taipei Medical University, Taiwan
- Postdoctoral Research Scientist, Department of Radiation Oncology, Columbia University Medical Center
- Ph.D., Cancer Biology, Taipei Medical University, Taiwan
- M.S., Biomedical Science, Taipei Medical University, Taiwan
- B.S., Medical Technology, Taipei Medical University, Taiwan