In Person Seminar: Computing Conscious Experience: Reinforcement Learning, Neuromodulatory Systems, and Dynamic Changes in Phenomenal Experience.

Kenneth T. Kishida, Ph.D.
Associate Professor
Physiology and Pharmacology
Wake Forest University School of Medicine
In Person Seminar: Computing Conscious Experience: Reinforcement Learning, Neuromodulatory Systems, and Dynamic Changes in Phenomenal Experience
Date: Nov. 8, 2023
Time: 9:30 a.m.
About this Seminar
Dr. Kishida and his research team seek a theoretical account of ‘how conscious phenomenal experience comes to be’. Such a theory should be founded in neurobiological and behavioral data and ought to yield engineerable solutions for the spectrum of psychiatric and neurological burdens that plague human mental (and physical) experience. Recent advances in the ability to monitor dopamine release in the human brain (with sub-second temporal resolution) while participants express adaptive behavior and report how they subjectively feel suggest a novel hypothesis about how the contents and context of conscious experience come to be laden with subjective value and emotional affect. The team hypothesizes a “Dynamic Affective Core”, which combines ideas about network representations of the contents and context of experience with signals derived from computational reinforcement learning theory that can add and dynamically modulate the subjective phenomenal value of constantly changing information states. Dr. Kishida will present a brief overview of the supporting neuroscientific data including intracranial sub-second measurements of dopamine release in humans and computational principles involved, but also discuss gaps in our understanding and future directions. The lab hopes to circumscribe the challenge of characterizing the neurobiological mechanisms that give rise to conscious experience in humans and provide a path forward for investigating disorders of human experience like mood disorders and substance use and addiction disorders.
You May Also Be Interested In...
-
Home ItemSuicide by Firearm in the United States: A Collaborative Path for Prevention , home
March 6, 2025, 5:30 p.m. (Reception at 5 p.m.) | Marian Betz, M.D., M.P.H. Professor, Departments of Epidemiology and Emergency Medicine, Deputy Director, Injury & Violence Prevention Center, University of Colorado School of Public Health; Member, National Academy of Medicine | Maury Strauss Distinguished Public Lecture
-
Home ItemThinking the Right Thoughts , home
Nathaniel Daw, Ph.D., Professor, Computational and Theoretical Neuroscience, Department of Psychology, Princeton University | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
-
Home ItemThe Emergence of Network Activity Patterns - An Early Window to Autism Spectrum Disorder , home
March 14, 2025, 11:00 a.m. | Natalia De Marco Garcia, Ph.D., Associate Professor, Department of Neuroscience, The Brain and Mind Research Institute, Weill Cornell Medical College | Co-Sponsored by the Center for Neurobiology Research, Fralin Biomedical Research Institute
-
Home ItemIntegration of Sensory, Metabolic and Neural Signals in the Determination of Food Choices and How Dysregulation of These Systems Contributes to Obesity, Diabetes and Cognitive Impairment , home
March 21, 2025, 11:00 a.m. | Dana M. Small, Ph.D., Professor, Department of Psychiatry and Psychology, Director, Modern Diet and Physiology Research Center, Yale School of Medicine | Co-Sponsored by the Center for Health Behaviors Research and the Addiction Recovery Research Center, Fralin Biomedical Research Institute
-
Home ItemSocial Learning in Borderline Personality Disorder , home
April 4, 2025, 11:00 a.m. | Sarah Fineberg, M.D., Ph.D., Assistant Professor, Department of Psychiatry, Yale School of Medicine | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research
-
Home ItemBringing Precision Medicine to Psychiatry , home
April 10, 2025, 5:30 p.m. (Reception at 5 p.m.) | Jordan Smoller, M.D., Sc.D., MGH Trustees Endowed Chair in Psychiatric Neuroscience; Professor of Psychiatry, Harvard Medical School; Professor of Epidemiology, T.H. Chan Harvard School of Public Health; Director, Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital | Maury Strauss Distinguished Public Lecture