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In Person Special Seminar: Involvement of Non-canonical Inflammatory Response in Tissue Dysfunction of Several Chronic Diseases

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Juan Saez, Ph.D.

Juan Saez, Ph.D.

Professor of Neuroscience
Director, Interdisciplinary Neuroscience Center
University de Valparaiso, Chile

Member, National Academy of Sciences 
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In Person Seminar: Involvement of Non-canonical Inflammatory Response in Tissue Dysfunction of Several Chronic Diseases

Date: Jan. 23, 2024

Time:  11 a.m.

In-person: Room G101 A/B, 4 Riverside Circle

Virtual: Join via Zoom

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About this Seminar

Most chronic diseases present inflammation but their therapy does not include anti-inflammatory compounds (i.e., Alzheimer's disease, dysferlinopathy, diabetes). One possible explanation for not including them is that long-term treatment with available anti-inflammatory drugs causes tissue dysfunctions. Another explanation could be that the inflammatory response of several chronic diseases is not directly mediated by the canonic responses of the immune system. Possible mediators of such responses are non-selective channels such as connexin and pannexin hemichannels. Lately, inhibitors of these channels have been shown to reduce the deleterious progression of certain diseases or even allow complete recovery of the affected organs. 

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