Special Seminar: Exploring the Role of Lactate as a Metabolic Signal in Mitochondrial Biogenesis
Kenya Takahashi, Ph.D.
Assistant Professor
Department of Sports Sciences
Graduate School of Arts and Sciences
The University of Tokyo
Exploring the Role of Lactate as a Metabolic Signal in Mitochondrial Biogenesis
Date: Nov. 18, 2024
Time: 11 a.m.
About this Seminar
Our understanding of lactate has changed drastically in recent years. Previously, lactate was considered merely a metabolic waste product and a cause of fatigue during exercise. However, it is now recognized as a valuable carbohydrate fuel source that is shuttled between different types of cells through specific transport proteins. Emerging evidence also suggests that lactate exerts myokine-like effects, mediating physiological adaptations across various tissues. In this seminar, Dr. Takahashi will present his recent work, which highlights the potential of lactate as a signaling molecule for mitochondrial adaptation in skeletal muscle.