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In Person at CNRIC: The Blood-Tumor Barrier: New Perspectives on Drug Delivery and Clinical Relevance

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Sadhana Jackson, M.D.

Sadhana Jackson, M.D.

Developmental Therapeutics and Pharmacology Unit
Surgical Neurology Branch
National Institute of Neurological Disorders and Stroke
National Institutes of Health

Pioneers in Biomedical Research Seminar: The Blood-Tumor Barrier: New Perspectives on Drug Delivery and Clinical Relevance

Date: Nov. 9, 2023

Time: 11 a.m. - 12 p.m.

About this Seminar

One of the major obstacles to effectively treating central nervous system (CNS) tumors is the integrity of the blood-brain barrier (BBB). The BBB prevents systemic drug delivery from reaching the brain and brain tumor tissue. While previous studies have mainly focused on circumventing the BBB, very few agents or mechanisms have been explored that modulate the tumor microenvironment to enhance effective therapies for malignant brain tumors. This presentation focuses on our current understanding of the heterogeneity of BBB permeability among malignant tumor cells and manipulation of the supportive BBB which aids in tumor growth.

Additional Details

This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Cancer Research Group. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.

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