Virginia Tech® home

In Person at CNRIC: The Blood-Tumor Barrier: New Perspectives on Drug Delivery and Clinical Relevance

Insert your title here

Sadhana Jackson, M.D.

Sadhana Jackson, M.D.

Investigator
Developmental Therapeutics and Pharmacology Unit
Surgical Neurology Branch
National Institute of Neurological Disorders and Stroke
National Institutes of Health

Pioneers in Biomedical Research Seminar: The Blood-Tumor Barrier: New Perspectives on Drug Delivery and Clinical Relevance

Date: Nov. 9, 2023

Time: 11 a.m. - 12 p.m.

About this Seminar

One of the major obstacles to effectively treating central nervous system (CNS) tumors is the integrity of the blood-brain barrier (BBB). The BBB prevents systemic drug delivery from reaching the brain and brain tumor tissue. While previous studies have mainly focused on circumventing the BBB, very few agents or mechanisms have been explored that modulate the tumor microenvironment to enhance effective therapies for malignant brain tumors. This presentation focuses on our current understanding of the heterogeneity of BBB permeability among malignant tumor cells and manipulation of the supportive BBB which aids in tumor growth.

Additional Details

This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Cancer Research Group. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.

You May Also Be Interested In...

  • Home Item
    A Ribocentric View of Muscle Proteostasis in Health and Disease: Novel Mechanisms Potential Therapeutic Opportunities
    A Ribocentric View of Muscle Proteostasis in Health and Disease: Novel Mechanisms Potential Therapeutic Opportunities , home

    Nov. 22, 2024, 11:00 a.m. | Gustavo A. Nader, Ph.D., FAPS, Professor, College of Health and Human Development; Chair, Molecular, Cellular, and Integrative Physiology; Huck Institutes of the Life Sciences; The Pennsylvania State University | Co-Sponsored by the Fralin Biomedical Research Institute Center for Exercise Medicine Research

  • Home Item
    Human Laboratory Evaluation of Cannabis Products
    Human Laboratory Evaluation of Cannabis Products , home

    Dec. 13, 2024, 11:00 a.m. | Ryan Vandrey, Ph.D., Professor, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine | Co-Sponsored by the Fralin Biomedical Research Institute Center for Health Behaviors Research and the Addiction Recovery Research Center

  • Home Item
    Mechanics of Convective Cell Motion
    Mechanics of Convective Cell Motion , home

    Jan. 10, 2025, 11:00 a.m. | Michael Murrell, Ph.D., Associate Professor, Department of Biomedical Engineering and Physics, Yale University | Co-Sponsored by the Fralin Biomedical Research Institute Cancer Research Center – Roanoke

  • Home Item
    The Role of Pericytes in Pulmonary Vascular Diseases
    The Role of Pericytes in Pulmonary Vascular Diseases , home

    Jan. 17, 2025, 11:00 a.m. | Vinicio de Jesus Perez, M.D., FCCP, FAHA, Assistant Professor, Wall Center Adult PH Clinic Division of Pulmonary and Critical Care Medicine, Stanford School of Medicine | Co-Sponsored by the Fralin Biomedical Research Institute Center for Vascular and Heart Research

  • Home Item
    Rethinking Human Health with AI: Solving Old Mysteries with Modern Tools
    Rethinking Human Health with AI: Solving Old Mysteries with Modern Tools , home

    Jan. 23, 2025, 5:30 p.m. (Reception at 5 p.m.) | Regina Barzilay, Ph.D., School of Engineering Distinguished Professor for AI and Health; AI Faculty Lead, Jameel Clinic; MIT Computer Science & Artificial Intelligence Lab; MacArthur Fellow; Member, National Academy of Engineering, American Academy of Arts and Sciences, and the National Academy of Medicine | Maury Strauss Distinguished Public Lecture

  • Home Item
    Neural Circuits for Social Behaviors
    Neural Circuits for Social Behaviors , home

    Jan. 24, 2025, 11:00 a.m. | Marcelo de Oliveira Dietrich, M.D., Ph.D., Associate Professor, Department of Comparative Medicine and Neuroscience, Yale School of Medicine | Co-Sponsored by the Center for Neurobiology Research, Fralin Biomedical Research Institute