In Person Seminar: Prioritizing Individuals and Individual Differences in the Study of Children with Neurodevelopmental Disorders
Bradley Schlaggar, M.D., Ph.D.
President and Chief Executive Officer,
Zanvyl Krieger Faculty Endowed Chair
Kennedy Krieger Institute
Professor
Department of Neurology and Department of Pediatrics
Johns Hopkins University School of Medicine
Pioneers in Biomedical Research Seminar: Prioritizing Individuals and Individual Differences in the Study of Children with Neurodevelopmental Disorders
Date: Jan. 27, 2023
Time: 11 a.m. - 12 p.m.
About this Seminar
The human central nervous system constitutes, arguably, the most complex biological system known. The myriad and heterogeneous clinical manifestations of disorders of the developing nervous system, both rare and common, reflect that complexity. Commonly, the study of typical and atypical neurodevelopment embraces central tendency assumptions and approaches to investigation. However, if we are to move effectively towards a precision medicine for neurodevelopmental disorders, we will need to shift our approach to methodologies that afford us an individual-level analysis. Dr. Schlaggar's talk, organized into two sections, will first assess the utility of functional MRI to investigate the development and plasticity of brain systems at the group- and individual-level of analysis. The discussion will then evaluate the reliance on central tendency-based approaches to investigating the etiology and treatment of developmental brain dysfunction and make the case for attending to heterogeneity in study design and clinical care.
Additional Details
This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Center for Human Neuroscience Research. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.
You May Also Be Interested In...
-
Home ItemIn Person at CNRIC: Hyperactivation of an RNA Binding Protein by Cancer-associated Mutations , home
April 19, 11:00 a.m., Collaboratory, Children's National Research and Innovation Campus, Washington, D.C. | Daniel Dominguez, Ph.D., Assistant Professor, Pharmacology, UNC School of Medicine | Co-Sponsored by the Fralin Biomedical Research Institute Cancer Research Center (DC)
-
Home ItemIn Person Seminar: Our Mass Spectrometry Screening Studies in the Mouse and Human Hearts in Health and Disease , home
April 26, 2024, 11 a.m. | Anthony Gramolini, Ph.D., Professor, Physiology and Translational Biology and Engineering, Ted Rogers Centre for Heart Research, University of Toronto | Co-Sponsored by the Fralin Biomedical Research Institute Center for Vascular and Heart Research
-
Home ItemIn Person Seminar: Regulation of Mitochondrial Parameters in Skeletal Muscle , home
May 3, 2024, 11:00 a.m. | Glenn Rowe, Ph.D., Associate Professor of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham | Co-Sponsored by the Fralin Biomedical Research Institute Center for Exercise Medicine Research
-
Home ItemPlanning the Future of Environmental Health Sciences , home
May 9, 2024, 5:30 p.m. (Reception at 5 p.m.) | Rick Woychik, Ph.D., Director, National Institute of Environmental Health Sciences, National Institutes of Health | Maury Strauss Distinguished Public Lecture
-
Home ItemIn Person Seminar: Flavors in Tobacco and Nicotine Products: Science-based Regulation , home
May 10, 2024, 11:00 a.m. | Suchitra Krishnan-Sarin, Ph.D., Albert E. Kent Professor of Psychiatry, Yale School of Medicine | Co-Sponsored by the Fralin Biomedical Research Institute Center for Health Behaviors Research and the Addiction Recovery Research Center
-
Home ItemCANCELLED: In Person Seminar: Sex Influences on Brain and Body: An Issue That is Here to Stay , home
May 17, 2024, 11:00 a.m. | Larry Cahill, Ph.D., Professor, Neurobiology and Behavior, University of California, Irvine | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research