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In Person Seminar: Genetic Drivers in Pancreatic Ductal Adenocarcinoma

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Azeddine Atfi, Ph.D.

Professor and Chair
Cellular and Molecular Pathogenesis Division, Department of Pathology
Cancer Biology Program, Massey Cancer Center
Virginia Commonwealth University

Pioneers in Biomedical Research Seminar: Genetic Drivers in Pancreatic Ductal Adenocarcinoma

Date: Jan. 13, 2023

Time: 11 a.m. - 12 p.m.

Location: Fralin Biomedical Research Institute at VTC, Room G101A/B, 4 Riverside Circle, Roanoke, Virginia

Virtual attendance:  Join via Zoom.

About this Seminar

Pancreatic ductal adenocarcinoma (PDAC) is the fourth-leading cause of cancer-related deaths worldwide and one of the most aggressive human malignancies. Although the current model posits that hyper-activation of oncogenic KRAS signaling represents an essential initiating event in PDAC, a substantial fraction of PDAC tumors harbor wild-type KRAS, hinting at the existence of alternative driver events. In this seminar, Dr. Atfi will discuss how to combine human genomics with genetic-engineered mouse models to identify the long sought-after genetic drivers in PDAC patients with normal KRAS signaling.  

Additional Details

This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Cancer Research Group. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.

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