Opposing Activities of Chromatin Modifiers in Balancing Stem Cell Division, Differentiation, and Death
Jamy Peng, Ph.D.
Associate Member
Department of Developmental Neurobiology
Comprehensive Cancer Care Center
St. Jude Children's Research Hospital
Pioneers in Biomedical Research Seminar: Opposing Activities of Chromatin Modifiers in Balancing Stem Cell Division, Differentiation, and Death
Date: Oct. 7, 2022
Time: 11 a.m. - 12 p.m.
About this Seminar
Neural stem cell division, neurogenesis, and gliogenesis give rise to all cells in the brain. Dr. Peng's lab studies the modifiers of histone H3 lysine 27 (H3K27), which regulate genetic programs for neural stem cell amplification and differentiation. Dysfunction in H3K27 modifiers lead to developmental disorders and pediatric brain tumors. The lab has uncovered regulators of these H3K27 modifiers that control stem cell division, differentiation, and death. These advances illuminate epigenetic regulation of neural stem cells and pathogenic mechanisms in brain defects and malignancy.
Additional Details
This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Cancer Research Group. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.
You May Also Be Interested In...
-
Home ItemIn Person at CNRIC: Hyperactivation of an RNA Binding Protein by Cancer-associated Mutations , home
April 19, 11:00 a.m., Collaboratory, Children's National Research and Innovation Campus, Washington, D.C. | Daniel Dominguez, Ph.D., Assistant Professor, Pharmacology, UNC School of Medicine | Co-Sponsored by the Fralin Biomedical Research Institute Cancer Research Center (DC)
-
Home ItemIn Person Seminar: Our Mass Spectrometry Screening Studies in the Mouse and Human Hearts in Health and Disease , home
April 26, 2024, 11 a.m. | Anthony Gramolini, Ph.D., Professor, Physiology and Translational Biology and Engineering, Ted Rogers Centre for Heart Research, University of Toronto | Co-Sponsored by the Fralin Biomedical Research Institute Center for Vascular and Heart Research
-
Home ItemIn Person Seminar: Regulation of Mitochondrial Parameters in Skeletal Muscle , home
May 3, 2024, 11:00 a.m. | Glenn Rowe, Ph.D., Associate Professor of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham | Co-Sponsored by the Fralin Biomedical Research Institute Center for Exercise Medicine Research
-
Home ItemPlanning the Future of Environmental Health Sciences , home
May 9, 2024, 5:30 p.m. (Reception at 5 p.m.) | Rick Woychik, Ph.D., Director, National Institute of Environmental Health Sciences, National Institutes of Health | Maury Strauss Distinguished Public Lecture
-
Home ItemIn Person Seminar: Flavors in Tobacco and Nicotine Products: Science-based Regulation , home
May 10, 2024, 11:00 a.m. | Suchitra Krishnan-Sarin, Ph.D., Albert E. Kent Professor of Psychiatry, Yale School of Medicine | Co-Sponsored by the Fralin Biomedical Research Institute Center for Health Behaviors Research and the Addiction Recovery Research Center
-
Home ItemCANCELLED: In Person Seminar: Sex Influences on Brain and Body: An Issue That is Here to Stay , home
May 17, 2024, 11:00 a.m. | Larry Cahill, Ph.D., Professor, Neurobiology and Behavior, University of California, Irvine | Co-Sponsored by the Fralin Biomedical Research Institute Center for Human Neuroscience Research