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In Person Seminar: Building and Maintaining Biological Tubes

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Ondine Cleaver, Ph.D.

Ondine Cleaver, Ph.D.

Molecular Biology
University of Texas Southwestern Medical Center

Pioneers in Biomedical Research Seminar: Building and Maintaining Biological Tubes

Date: Jan. 19, 2024

Time: 11 a.m. - 12 p.m.

About this Seminar

Many organs such as pancreas, kidney and lung, and tissues such as blood vessels, are made of biological tubes. Dr. Cleaver's lab studies the formation of blood vessels from endothelial cells and how both the cytoskeleton and cell-cell junctions must dynamically reorganize during this "tubulogenesis" event. Remarkably, the lab has identified a similar molecular machinery that is required to drive epithelial cells of the pancreatic primordium to forming lumens and branches. Together the team's work leverages cell biology, biomechanics and genetics to better understand the events that underlie organogenesis. 

Additional Details

This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Center for Vascular and Heart Research. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.

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