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Restoring Angiogenesis in Pulmonary Arterial Hypertension: A Role for Wnt Signaling Pathways?

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Vinicio de Jesus Perez, M.D., FCCP, FAHA headshot

Vinicio de Jesus Perez, M.D., FCCP, FAHA

Professor of Medicine
Wall Center Adult PH Clinic Division of Pulmonary and Critical Care Medicine
Associate Dean of MD Admissions
Director of Faculty and Fellow Diversity and Inclusion
Stanford School of Medicine
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Pioneers in Biomedical Research Seminar

Restoring Angiogenesis in Pulmonary Arterial Hypertension: A Role for Wnt Signaling Pathways?

Date: Jan. 17, 2024

Time: 11 a.m. - 12 p.m.

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About this Seminar

Pulmonary arterial hypertension (PAH) is a life-threatening disorder of the pulmonary circulation associated with loss and impaired regeneration of micro-vessels. Pericytes are highly specialized cells that interact with endothelial cells to promote vessel survival, but little is known about their role in the repair and regeneration of pulmonary micro-vessels.  Understanding the mechanisms that orchestrate endothelial-pericyte interactions can provide insight into the mechanism behind progressive small vessel loss in PAH and open new therapeutic opportunities to promote regeneration of lost vessels, prevent progression, and improve clinical outcomes for patients afflicted with this devastating disease.

Additional Details

This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Center for Vascular and Heart Research. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.

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