Unraveling Mechanisms of BCAA Compartmentalization and Crosstalk in Cardiometabolic Disease
Phillip J. White, Ph.D.
Associate Professor of Medicine
Division of Endocrinology, Metabolism, & Nutrition
Duke Molecular Physiology Institute
Duke University School of Medicine
Pioneers in Biomedical Research Seminar
Unraveling Mechanisms of BCAA Compartmentalization and Crosstalk in Cardiometabolic Disease
Date: May 29, 2026
Time: 11 a.m. to noon
In-person: Room G101 A/B, 4 Riverside Circle, Roanoke, Virginia
Virtual: Watch via Zoom
About this Seminar
Branched-chain amino acid (BCAA) metabolism is highly compartmentalized and involves sensing and trafficking of BCAA and their keto acid metabolites across organelles, cells, and tissues. The regulatory enzymes governing BCAA metabolism also interface with other pathways involved in lipid, glucose, and protein homeostasis. This talk will cover recent identification of the carriers governing branched-chain keto acid transport and new insights into molecular mechanisms that facilitate cross-talk between BCAA, glucose, lipid, and protein metabolism and their relevance for cardiometabolic health.
Additional Details
This is a free event hosted by the Fralin Biomedical Research Institute and co-sponsored by the institute's Center for Exercise Medicine Research. The Pioneers in Biomedical Research Seminar Series, which runs annually from September to May, has featured leading biomedical researchers from throughout the country since the program began in 2012. The lectures are also open to all members of the Virginia Tech community including graduate students, undergraduates, faculty, and staff, as well as the public.
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